Protein Alignment Rdl and glra1

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_021336638.1
• Gene: glra1 / 30676
• ZFINID: ZDB-GENE-991117-1
• Length: 457
• Species: Danio rerio
• Alignment Length: 591
• Identity: 177/591 - (29%)
• Similarity: 258/591 - (43%)
• Gaps: 174/591 - (29%)

  Fly    23 IWLAI---NMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNY------ 78
            :|..|   ::|...|....|....:..:.....::|.|:          .||.|:|||:
Zfish     8 LWETIVFFSLAASQQAAARKAASPMPPSEFLDKLMGKVS----------GYDARIRPNFKDPQGS 62

  Fly    79 -------GGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEF 136
                   .||||.|...:::.|..|::|..||:.::.:.||.|.||||||.:.|. ::|.:....
Zfish    63 KSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD-DSLDLDPSM 126

  Fly   137 IKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHI 201
            :.:||.||.||.|||.:.||..||.|:.:|:..:|::..|||:|:..:|||:|:.||||.|.|.:
Zfish   127 LDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIM 191

  Fly   202 EIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQ-RATEINLTTGNYSRLACEIQFVR 265
            ::|||||||.|:.:.| |...:|.::..:.||||.:...:. |....:..||.::.:.......|
Zfish   192 QLESFGYTMNDLIFEW-DEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLER 255

  Fly   266 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSI 330
            .|||||||:||||.||||:||||||:|.:|.||||.||:||||||||..|.:.|:|||:||||:|
Zfish   256 QMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAI 320

  Fly   331 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANV 395
            |:::..|.:.||::|||||.|.:                 ||.|.|:.|
Zfish   321 DIWMAVCLLFVFSALLEYAAVNF-----------------IARQHKELL---------------- 352

  Fly   396 GGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQ 460
                                                                             
Zfish   353 ----------------------------------------------------------------- 352

  Fly   461 NVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPG-----QGGGPPGG 520
                             ||:..  :.|.|    |:....||....::|.||.     .|....|.
Zfish   353 -----------------RFQRR--RRHLK----EDEAGDGRFSFAAYGMGPACLQAKDGMAIKGN 394

  Fly   521 GGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNL 585
            .........|||                   |.|:::.||.......||..||:.||:.|:.||:
Zfish   395 NNNAPTSTNPPE-------------------KTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNI 440

  Fly   586 MYWIIY 591
            .|||.|
Zfish   441 FYWITY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	66/183 (36%)
		Cys-loop	185..199	CDD:349809	9/13 (69%)
		Neur_chan_memb	274..588	CDD:460753	83/318 (26%)
glra1	XP_021336638.1	LIC	7..446	CDD:273305	176/589 (30%)