Protein Alignment Rdl and Gabra5

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_058991.2
• Gene: Gabra5 / 29707
• RGDID: 61859
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 157/540 - (29%)
• Similarity: 239/540 - (44%)
• Gaps: 137/540 - (25%)

  Fly    62 ILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPG 126
            |||.....||.|:||..|....:|...:||.|...:|:.:|::|:|.:|||.|.|.||.: |.|
  Rat    52 ILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRF-KGP- 114

  Fly   127 VETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQY 191
            ::.|.:.:.....||.|||||.|.|:|..|..||.|:.:|:...|::..::||||:|.|||.|:.
  Rat   115 MQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLED 179

  Fly   192 FPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSE--VELPQFRVLGHRQRATEINLTTGNY 254
            ||||...|.::..|:.|...::.|.|.:|.:...:.:|  ..|.|:.::|.......|:.:||.|
  Rat   180 FPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEY 244

  Fly   255 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNA 319
            :.:.......|.:||::||.|:|..:.||:|.|||||||.:.|||...|||||||||||..|...
  Rat   245 TIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARN 309

  Fly   320 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR-IQMRKQRFMAIQKIAEQKKQQLDGAN 383
            :|||::|..::|.::..|:..||::|:|:|||.|..|| .....::.:...||.:::::.:
  Rat   310 SLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKERELI---- 370

  Fly   384 QQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTV 448
               .|.:.||...|                                     ..:| .|:.||:.:
  Rat   371 ---LNKSTNAFTTG-------------------------------------KLTH-PPNIPKEQL 394

  Fly   449 SNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQ 513
                                                                             
  Rat   395 ----------------------------------------------------------------- 394

  Fly   514 GGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPV 578
                |||.|...|           .|::.|......:.||.  .|.:     |.|||.||||||:
  Rat   395 ----PGGTGNAVG-----------TASIRASEEKTSESKKT--YNSI-----SKIDKMSRIVFPI 437

  Fly   579 CFVCFNLMYWIIYLHVSDVV 598
            .|..|||:||..||:...|:
  Rat   438 LFGTFNLVYWATYLNREPVI 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	61/184 (33%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	77/314 (25%)
Gabra5	NP_058991.2	LIC	15..450	CDD:455710	154/531 (29%)
		LGIC_ECD_GABAAR_A5	58..256	CDD:349839	67/199 (34%)
		Cys-loop	173..187	CDD:349839	8/13 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..414		11/112 (10%)