Protein Alignment Rdl and Gabrb3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_058761.2
• Gene: Gabrb3 / 24922
• RGDID: 2651
• Length: 473
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 184/547 - (33%)
• Similarity: 274/547 - (50%)
• Gaps: 122/547 - (22%)

  Fly    59 ISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRK 123
            :...:|.....||.|:||::|||||.||:.:.:.||..:|||.||:||..||:|:|.|.||||..
  Rat    37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG 101

  Fly   124 RPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMN 188
            .|  ..|::.:.....:|||||:|:|:|:|:.|..|..|..||:|..|::...:|:|.||:|.|:
  Rat   102 IP--LNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMD 164

  Fly   189 LQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGN 253
            |:.:|:|.|.|.:||||:|||..||.::||.|..:|.....:|||||.::.||..:..:...||.
  Rat   165 LRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGA 229

  Fly   254 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTN 318
            |.||:...:..|::||:::|.|:||.||.|:||||||:|.:|:.||||||:||||||||:.:...
  Rat   230 YPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLR 294

  Fly   319 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGAN 383
            ..||||.|||:||:||..|||.||.:|||||.|.|:......::|:     |:||:..:..:..:
  Rat   295 ETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK-----KLAEKTAKAKNDRS 354

  Fly   384 QQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTV 448
            :.:.|                                             ...:||
  Rat   355 KSEIN---------------------------------------------RVDAHG--------- 365

  Fly   449 SNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPK---AHSKGGTLENTVNGGRGGPQSHGPG 510
                    ||          ::.|:      .||:..   |.|.|.|..:.::....|.|.....
  Rat   366 --------NI----------LLAPM------DVHNEMNEVAGSVGDTRNSAISFDNSGIQYRKQS 406

  Fly   511 -PGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVP---AHLLHPGKVKKVK-----DINKLLGITPS 566
             |.:|.|...|                 :.::|   .||.......|:|     |:|.
  Rat   407 MPKEGHGRYMG-----------------DRSIPHKKTHLRRRSSQLKIKIPDLTDVNA------- 447

  Fly   567 DIDKYSRIVFPVCFVCFNLMYWIIYLH 593
             ||::||||||..|..|||:||:.|::
  Rat   448 -IDRWSRIVFPFTFSLFNLVYWLYYVN 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	75/182 (41%)
		Cys-loop	185..199	CDD:349809	6/13 (46%)
		Neur_chan_memb	274..588	CDD:460753	92/325 (28%)
Gabrb3	NP_058761.2	LIC	10..471	CDD:273305	183/543 (34%)