Protein Alignment Rdl and lgc-37

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 163/557 - (29%)
• Similarity: 244/557 - (43%)
• Gaps: 147/557 - (26%)

  Fly    62 ILDSFSVSYDKRVRP-NYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRK-R 124
            :||:..::.||..|| |....|::|.|.:.:.|:..:||..|:|:||.||||.|.|.|||:.. .
 Worm    47 VLDTILLNQDKNFRPVNPDNSPLQVEVDISIRSMGPVSEQNMEFSLDCYFRQKWLDRRLAFTPIN 111

  Fly   125 PGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNL 189
            |....:.:.|:.:|:||:|||:..|.::||.|..|..|...||...|.:..|.||||.:.|.|.|
 Worm   112 PSKPEIPLASKMLKDIWIPDTYIRNGRKSYLHTLTVPNILFRVRSDGQVHVSQRLTIRSRCQMFL 176

  Fly   190 QYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLG---HRQRATEINLTT 251
            :.||||.|.|.||:.|.||..:|:.|.|:|......|.:  .|.|::||.   ..:..::...:.
 Worm   177 KKFPMDTQACPIEVGSLGYFSKDVVYKWKDVELDAKMGN--TLSQYQVLSLSKSERNVSDFRFSD 239

  Fly   252 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSS 316
            .|.|.|....:..|..|||::|||.|..|:|::||||||:|:.|:||||:||:.|||:|:|:...
 Worm   240 RNISVLNVYFKLQRQQGYYILQIYTPCTLVVVMSWVSFWINKEASPARVSLGIMTVLSMSTIGFG 304

  Fly   317 TNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDG 381
            ....|||:|:..::|||:.||||.:||:::|||.:.| |:.:.:|||            ...|.|
 Worm   305 LRTDLPKVSHSTALDVYILTCFVFLFAAMVEYAVINY-AQIVYIRKQ------------IHDLKG 356

  Fly   382 ANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQ 446
            ..|       |..:|.....|:                   ||          |...........
 Worm   357 LEQ-------NTAMGQMFTAGL-------------------MG----------ARRRDTIQVDDL 385

  Fly   447 TVSN-----------RPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGG 500
            ||..           :.:.|.:.|.|..         :|..:..|....|.     ||.|
 Worm   386 TVEKEEARLKAVPWWKKLCFKDEQGNTS---------MFYRMAVKAAIAKK-----TLRN----- 431

  Fly   501 RGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITP 565
                                              |||...|                ||
 Worm   432 ----------------------------------GDPAEVV----------------NK------ 440

  Fly   566 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDL 602
              ||.:|::.||..::.||:.||:.|||   ::.|::
 Worm   441 --IDNFSKLAFPTLYIIFNVFYWVAYLH---LIPDEI 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	66/186 (35%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	78/324 (24%)
lgc-37	NP_499662.2	LIC	44..464	CDD:455710	159/544 (29%)
		LGIC_ECD	68..254	CDD:475126	67/187 (36%)