Protein Alignment Rdl and Gabrg1

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Alignment Length: 541
• Identity: 156/541 - (28%)
• Similarity: 235/541 - (43%)
• Gaps: 138/541 - (25%)

  Fly    55 GDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRL 119
            ||  |:.||:|....||.::||:.|..|..:...:||.||..:..:.|::|:|..|.|.|.|.||
Mouse    62 GD--ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124

  Fly   120 AYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITAS 184
            .:...  ::.|.:.|..:..||:|||||.|.::|..|..||.|..:|:...|.:..::||||.|.
Mouse   125 KFNST--MKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAE 187

  Fly   185 CPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINL 249
            |.:.|..||||...|.:|..|:||...:|.|.|:.....|.......|.||..:|.| .:|||:.
Mouse   188 CYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLR-NSTEISH 251

  Fly   250 T-TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTL 313
            | :|:|..:.......|.|||:.||.|||..|.|::||||||:|::|.|||.:||:|||||||||
Mouse   252 TISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTL 316

  Fly   314 MSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQ 378
            .:....:|||:|||.::|:::..||:.|||:|:||.|:.|.....:.:..|...::
Mouse   317 STIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRGRKLK--------- 372

  Fly   379 LDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHA 443
                |:..|:|            |:..|....|...:::..|     |..:|:
Mouse   373 ----NKTSASP------------GLHAGSTLIPMNSISLPQG-----EDDYGY------------ 404

  Fly   444 PKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHG 508
                            |.:..:.|:.....|.:.|          .|...|..::
Mouse   405 ----------------QCLEGKDCTSFFCCFDDCR----------TGSWREGRIH---------- 433

  Fly   509 PGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSR 573
                                                                  |..:.||.|||
Mouse   434 ------------------------------------------------------IRIAKIDSYSR 444

  Fly   574 IVFPVCFVCFNLMYWIIYLHV 594
            |.||..|..|||:||:.||::
Mouse   445 IFFPTAFALFNLVYWVGYLYL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	61/183 (33%)
		Cys-loop	185..199	CDD:349809	6/13 (46%)
		Neur_chan_memb	274..588	CDD:460753	73/313 (23%)
Gabrg1	NP_034382.2	LIC	66..462	CDD:455710	151/530 (28%)
		LGIC_ECD_GABAAR_G	88..269	CDD:349801	61/183 (33%)
		Cys-loop	188..202	CDD:349801	6/13 (46%)