Protein Alignment Rdl and Gabre

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_059065.2
• Gene: Gabre / 14404
• MGIID: 1330235
• Length: 916
• Species: Mus musculus
• Alignment Length: 570
• Identity: 143/570 - (25%)
• Similarity: 231/570 - (40%)
• Gaps: 138/570 - (24%)

  Fly    43 TVQAAT--GGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFT 105
            ||...|  .||.:   ...|.||::...:||.::||..|..|..|.|.:.|.|:..:|...|:::
Mouse   467 TVDCMTERPGGKL---TRASRILNTILSNYDHKLRPGIGEKPTVVTVEVIVNSLGPISTPDMEYS 528

  Fly   106 LDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHS 170
            :|..|.|.|.|.||.|...  .|||.:....:..:|:|||||.|.|::..:..|..|:...:|..
Mouse   529 IDIIFHQTWYDERLRYNDT--FETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALIHKD 591

  Fly   171 GSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQF 235
            |.:..|:|:||.|.|.:::..||||...|.:...||.|...::.|.|.:....:...:..:|.:|
Mouse   592 GKVLYSVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDDSEMIYKWENFKLEINAKNTWKLLEF 656

  Fly   236 RVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARV 300
            ...|...:...|:...|::..:.......|..|:.:.|.|:||.:..::||||||:...|..||.
Mouse   657 DFTGVNNKTEIISTPFGDFMVMTFFFNVSRRFGFIVFQNYVPSSVTTMLSWVSFWIKIEAAAARA 721

  Fly   301 ALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF 365
            ::||::||||.||.:.:....|::||:.::|.|:..|||:.|.:|||:|.:.::.         :
Mouse   722 SVGVSSVLTMATLGTLSCKNFPRVSYLTALDFYIAICFVLCFCTLLEFAVLNFLT---------Y 777

  Fly   366 MAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHG 430
            ..|::.|..|..||  ....:||....|
Mouse   778 NNIKRQASLKVYQL--PTNSRANARTRA------------------------------------- 803

  Fly   431 HGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLEN 495
               .|.:.....|..:.           ||.|..  |.||          .::          ||
Mouse   804 ---RARTRARARARARQ-----------QQEVFV--CEIV----------TYE----------EN 832

  Fly   496 TVNGGRGGPQSHGPG-PGQGGG---------------PPGGGGGGGGGGGPPEGGGDPEAAVPAH 544
            ...|.:..|:|..|. |.:..|               .||           .|||......:..|
Mouse   833 AEEGYQWSPRSRRPQCPWRRCGRSYVCFRVLRKYFCMAPG-----------CEGGSWQRGRICIH 886

  Fly   545 LLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 594
            :..                    :|.|||::||:.|..||::||:|.|::
Mouse   887 VYR--------------------LDNYSRVLFPITFFFFNVLYWLICLNL 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	50/182 (27%)
		Cys-loop	185..199	CDD:349809	5/13 (38%)
		Neur_chan_memb	274..588	CDD:460753	72/329 (22%)
Gabre	NP_059065.2	LIC	484..912	CDD:455710	135/544 (25%)
		LGIC_ECD	506..687	CDD:475126	50/182 (27%)