Protein Alignment Rdl and Lcch3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_061518383.1
• Gene: Lcch3 / 1272239
• VectorBaseID: AGAMI1_002473
• Length: 497
• Species: Anopheles gambiae
• Alignment Length: 597
• Identity: 188/597 - (31%)
• Similarity: 281/597 - (47%)
• Gaps: 147/597 - (24%)

  Fly    27 INMALIAQETGHKRIHTVQAATGGGSMLGDV--NISAILDSFSVSYDKRVRPNYGGPPVEVGVTM 89
            :|.||       :.:|....|.|   .|.:|  .||.||:    .||.|:|||:||.|:.||:.:
Mosquito    15 LNNAL-------RSVHQRSMAAG---RLENVTQTISRILE----GYDIRLRPNFGGEPLHVGMDL 65

  Fly    90 YVLSISSLSEVKMDFTLDFYFRQFWTDPRLAY----------RKRPGV---------ETLSVGSE 135
            .:.|..::|||.||:|:..|..|:|.|.|||:          :.:.|.         :.:::..:
Mosquito    66 TIASFDAISEVNMDYTITMYLNQYWKDERLAFNAFALWGDNQKDQTGEIMIEDDGANDVITLSGD 130

  Fly   136 FIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCH 200
            |.:.||||||||.|:|.|:.|..|..|:.:|:...|::|..:|.|.|.:|.|:|.|:|:|.|.|.
Mosquito   131 FAEKIWVPDTFFANDKNSFLHDVTERNKLVRLAGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCT 195

  Fly   201 IEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVR 265
            :||||:|||:.|:..:||.  :.:....|.|||||.::|:.....:..|.||.|.||:...:..|
Mosquito   196 VEIESYGYTVSDVVMYWRS--TPIRGVEEAELPQFTIIGYETNDRKEKLATGIYQRLSLSFKLQR 258

  Fly   266 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSI 330
            ::||::.|.|:||.|||::||||||:|..||.||||||:||||||||:.:...::||:|||||:|
Mosquito   259 NIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAI 323

  Fly   331 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANV 395
            |:||..|||.|||:|||||.|.|.....:.:|:     .|..::.::::.|..::
Mosquito   324 DIYLVMCFVFVFAALLEYAAVNYTYWGARAKKK-----SKKNKEAERKVFGKTEK---------- 373

  Fly   396 GGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQ 460
                                                                             
Mosquito   374 ----------------------------------------------------------------- 373

  Fly   461 NVGTRGCSIVGPL-FQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGG 524
               |..||....: .|::|.   .|.|..:.....||:........:..|...:.....|.....
Mosquito   374 ---TSTCSADDIIELQDIRM---SPIASLRNRHYSNTITTTDSVDSAKFPPSFRIARSYGSSNRS 432

  Fly   525 GGGGGPPEGGGDPEAAVPAHLLHPGK---------VKKVKDINKLLGITPSDIDKYSRIVFPVCF 580
            |.......|.|.|:      :||..|         :.|:||:|.        ||||||::|||.|
Mosquito   433 GLRYRSSRGQGRPK------MLHAIKRGASVIKASIPKIKDVNV--------IDKYSRVIFPVSF 483

  Fly   581 VCFNLMYWIIYL 592
            ..||..|||.|:
Mosquito   484 AAFNAGYWIFYV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	69/201 (34%)
		Cys-loop	185..199	CDD:349809	7/13 (54%)
		Neur_chan_memb	274..588	CDD:460753	90/323 (28%)
Lcch3	XP_061518383.1	None