Protein Alignment Rdl and LOC1270594

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_061518959.1
• Gene: LOC1270594 / 1270594
• VectorBaseID: AGAMI1_011195
• Length: 655
• Species: Anopheles gambiae
• Alignment Length: 614
• Identity: 189/614 - (30%)
• Similarity: 275/614 - (44%)
• Gaps: 103/614 - (16%)

  Fly    58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYR 122
            |||.:||:....||..:||::||||..:.|.:.|.|:..:|||.|.:::|.||||.|.|.|||:
Mosquito    61 NISELLDNLLRGYDNSIRPDFGGPPAVIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDRRLAF- 124

  Fly   123 KRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPM 187
             ....:||::....:..||.|||:|.|.||||.|..||.|:|:|::..|.:..|.||||.|.|||
Mosquito   125 -SGAQDTLALSISMLGRIWKPDTYFYNGKQSYLHTITTPNKFVRLYQDGRVLYSSRLTIKAGCPM 188

  Fly   188 NLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQF------------RVLGH 240
            ||:.||||.|.|.::..|||||..|:.|.|..|.::|.::.:::|.||            ||:.:
Mosquito   189 NLEDFPMDTQRCPLKFGSFGYTTNDVLYRWNSGRTAVTIADDMKLSQFDLVEWPAGNVTDRVVHN 253

  Fly   241 RQR--ATEIN----------------------------LTTGNYSRLACEIQFVRSMGYYLIQIY 275
            ...  ||.:|                            |....||.|.......|.||.:|||:|
Mosquito   254 TASAGATVLNGMGNADLELGLGLDGGVGRATGGEGNGKLYMSEYSMLLVSFHLQRHMGNFLIQVY 318

  Fly   276 IPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVM 340
            .|..|:|::|||||||||.||..||:||:|||||||.|.......|||:.|..::|.::...|..
Mosquito   319 GPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPYPTALDFFVFLSFGF 383

  Fly   341 VFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPG------ 399
            :||:::::|.|.|..|  ....:.:.::.::....    |..:..:..|:.|    |||
Mosquito   384 IFATIIQFAIVHYFTK--YGSGECYFSVDELTSSS----DDEDSDREAPDRN----GPGSSRAAQ 438

  Fly   400 ---GVGV-GPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHA----PKQTVSNRP-IGF 455
               .:.: ||.|..|..||........:....|.|..........|.:    |...:...| ..:
Mosquito   439 HHHSINIAGPAGTPGRCGGKRCSTITSISGAQGSGATDSRIIEVIPLSVCSFPLTPMRKTPKTSW 503

  Fly   456 SNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGG 520
            :::....|...|.:...       ...||  |:...|:|..  |..|.|............||..
Mosquito   504 TDVSCFGGGSSCGVEDS-------TTSDP--HASTSTVERA--GAYGAPIETATTSSSFASPPTT 557

  Fly   521 GGGGG------GGGGPPEGG--------GDPEAAVPAHLLHPGKV----KKVKDINKLLGITPSD 567
            ...||      |..|...||        ..|..|...|..:..:.    |:....|.:     |.
Mosquito   558 SALGGHHRRRSGAAGSTHGGVQQHHLTINAPLTASETHGTNGHRTRRRRKRAPRFNSV-----SK 617

  Fly   568 IDKYSRIVFPVCFVCFNLMYWIIYLHVSD 596
            ||:.|||.||:.|:..|:.||.:||..|:
Mosquito   618 IDRASRIFFPLLFLAINVFYWYLYLSRSE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	76/224 (34%)
		Cys-loop	185..199	CDD:349809	10/13 (77%)
		Neur_chan_memb	274..588	CDD:460753	89/346 (26%)
LOC1270594	XP_061518959.1	None