Protein Alignment Rdl and gabra3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_002939243.2
• Gene: gabra3 / 100494398
• XenbaseID: XB-GENE-992774
• Length: 538
• Species: Xenopus tropicalis
• Alignment Length: 583
• Identity: 170/583 - (29%)
• Similarity: 248/583 - (42%)
• Gaps: 146/583 - (25%)

  Fly    20 LLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNI-SAILDSFSVSYDKRVRPNYGGPPV 83
            |:.:.:.:.|.|:....|....|..:.......   ::.| :.|||.....||.|:||..|....
 Frog    82 LVALGILLRMCLLPAGKGLSAKHAPEVVDDSRD---NITIFTRILDRLLDGYDNRLRPGLGDSVT 143

  Fly    84 EVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFV 148
            ||...:||.|...:|:..|::|:|.:|||.|.|.||.: ..| :.||.:.:.....||.|||||.
 Frog   144 EVKTDIYVTSFGPVSDTDMEYTIDVFFRQSWLDERLKF-DGP-IRTLPLNNLLASKIWTPDTFFH 206

  Fly   149 NEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDI 213
            |.|:|..|..||.|:.:|:..:|::..::||||.|.|.|:|:.||||...|.::..|:.|...::
 Frog   207 NGKKSVAHNMTTPNKLLRLIDNGTLLYTMRLTIHAECTMHLEDFPMDVHACPLKFGSYAYPKTEV 271

  Fly   214 RYFWRDGLS-SVGMSSE-VELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYI 276
            .|.|.:|.: ||.::.: ..|.|:.:||.......|..:||.|..:.......|.:||::||.|:
 Frog   272 VYSWTNGSNKSVAVAPDGSRLNQYDLLGVAVGTETIRSSTGEYIVMTTHFHLKRKIGYFVIQTYL 336

  Fly   277 PSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMV 341
            |..:.||:|.|||||||.:.|||...|||||||||||..|...:|||::|..::|.::..|:..|
 Frog   337 PCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFMAVCYAFV 401

  Fly   342 FASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPG 406
            |::|:|:|||.|..||                  ....||...|:
 Frog   402 FSALIEFATVNYFTKR------------------GWAWDGKRGQE-------------------- 428

  Fly   407 GPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGF---SNIQQNVGTRGCS 468
                                            |.....|:     ||..   ||...|
 Frog   429 --------------------------------GQDFKKKE-----PIILAKKSNTTYN------- 449

  Fly   469 IVGPLFQEVRFKVHDP--KAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPP 531
            |||..:   ...:.:|  ...:|...|:                                   ||
 Frog   450 IVGTTY---TLNIKEPALATIAKSAALQ-----------------------------------PP 476

  Fly   532 EGGGDPEAAVPAHLLH-PGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 593
                 |....|.||.| |.:.||..:       :.|.|||.|||||||.|..|||:||..|::
 Frog   477 -----PPPLSPRHLEHKPMECKKTYN-------SVSRIDKISRIVFPVLFAIFNLVYWATYVN 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	63/184 (34%)
		Cys-loop	185..199	CDD:349809	7/13 (54%)
		Neur_chan_memb	274..588	CDD:460753	84/319 (26%)
gabra3	XP_002939243.2	LIC	121..525	CDD:455710	163/537 (30%)
		LGIC_ECD_GABAAR_A3	127..326	CDD:349837	69/200 (35%)
		Cys-loop	243..257	CDD:349837	7/13 (54%)