Protein Alignment Rdl and gabrg3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_002931686.2
• Gene: gabrg3 / 100494037
• XenbaseID: XB-GENE-6041774
• Length: 446
• Species: Xenopus tropicalis
• Alignment Length: 544
• Identity: 149/544 - (27%)
• Similarity: 229/544 - (42%)
• Gaps: 146/544 - (26%)

  Fly    56 DVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLA 120
            |.:.:.||:.....|||::||:.|..|..:.|.:||.||..:|.:.|::.:|.:|.|.|||.||.
 Frog    44 DTDATLILNKLLKEYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR 108

  Fly   121 YRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASC 185
            :...  ::.|::.|..:..||:|||.|.|.|.:..|..||.|:.:|:.:.|.|..::||||.|.|
 Frog   109 FNST--MKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAEC 171

  Fly   186 PMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLT 250
            .:.|..||||...|.:...|:||...::.|.||.............|.||..:|.|.....:..:
 Frog   172 QLQLHNFPMDEHSCPLIFSSYGYPREEMVYRWRKNSVETANQKSWRLYQFDFMGLRNTTEIVKTS 236

  Fly   251 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMS 315
            .|:|..:.......|.|||:.||.|||..|.|::||||||:.::|||||.|||:|||||||||.:
 Frog   237 AGDYIVMTVYFDLSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLST 301

  Fly   316 STNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLD 380
            ....:||::|||.::|:::..||:.|||:|:|||.:.|.:   ..:|.|       ..:||:.
 Frog   302 IARKSLPRVSYVTAMDLFVTVCFLFVFAALIEYAALNYYS---SCKKPR-------CTKKKKS-- 354

  Fly   381 GANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPK 445
                                               |..| :.|.|                 .|.
 Frog   355 -----------------------------------NYSV-LDMRP-----------------PPT 366

  Fly   446 QTVSNRPIGFSNIQQN-----VGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQ 505
            ....|..:.:...::.     :..:.|......:.|           .|.|:...    ||
 Frog   367 VITLNNSLYWQEFEEACVYECLDGKDCQSFFCCYDE-----------CKSGSWRR----GR---- 412

  Fly   506 SHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDK 570
                                                    :|               |...::|.
 Frog   413 ----------------------------------------IH---------------IDLLELDS 422

  Fly   571 YSRIVFPVCFVCFNLMYWIIYLHV 594
            |||:.||..|:.|||:||:.||::
 Frog   423 YSRVFFPTSFLLFNLVYWVGYLYL 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	57/182 (31%)
		Cys-loop	185..199	CDD:349809	6/13 (46%)
		Neur_chan_memb	274..588	CDD:460753	72/318 (23%)
gabrg3	XP_002931686.2	LIC	50..443	CDD:455710	146/533 (27%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	57/182 (31%)
		Cys-loop	171..185	CDD:349801	6/13 (46%)