Protein Alignment Rdl and gabra1

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_031754594.1
• Gene: gabra1 / 100490334
• XenbaseID: XB-GENE-6033338
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 534
• Identity: 155/534 - (29%)
• Similarity: 227/534 - (42%)
• Gaps: 137/534 - (25%)

  Fly    62 ILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPG 126
            |||.....||.|:||..|....||...::|.|...:|:..|::|:|.:|||.|.|.||.: |.|
 Frog    44 ILDRLLDGYDNRLRPGLGERVTEVNTDIFVTSFGPVSDHDMEYTIDVFFRQGWRDERLKF-KGP- 106

  Fly   127 VETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQY 191
            :..|.:.:.....||.|||||.|.|:|..|..|..|:.:|:...|::..::|||:.|.|||:|:.
 Frog   107 MTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLED 171

  Fly   192 FPMDRQLCHIEIESFGYTMRDIRYFW--RDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNY 254
            ||||...|.::..|:.||..::.|.|  ...||.|.......|.|:.:||....:..:..:||.|
 Frog   172 FPMDAHACPLKFGSYAYTRAEVVYSWTREPSLSVVVAEDGSRLNQYDLLGQTVASGIVQSSTGEY 236

  Fly   255 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNA 319
            ..:.......|.:||::||.|:|..:.||:|.|||||||.:.|||...|||||||||||..|...
 Frog   237 IVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARN 301

  Fly   320 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQ 384
            :|||::|..::|.::..|:..||::|:|:|||.|..||......:.:..:| .::.|..|...|.
 Frog   302 SLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEK-PKKVKDPLIKKNN 365

  Fly   385 QQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVS 449
            ..|:...|                                               :|    .|:.
 Frog   366 TYASATAN-----------------------------------------------YP----PTIP 379

  Fly   450 NRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQG 514
            ..| |.:.|                             :|..|:|         |:...|.|
 Frog   380 RDP-GLATI-----------------------------AKSATIE---------PKDIEPKP--- 402

  Fly   515 GGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVC 579
                                            .|.:.||.  .|.:     |.||:.|||.||:.
 Frog   403 --------------------------------KPAEPKKT--FNSV-----SKIDRLSRIAFPLL 428

  Fly   580 FVCFNLMYWIIYLH 593
            |..|||:||..||:
 Frog   429 FGTFNLVYWATYLN 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	61/184 (33%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	76/313 (24%)
gabra1	XP_031754594.1	LIC	11..440	CDD:455710	153/530 (29%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	65/194 (34%)
		Cys-loop	165..179	CDD:349835	8/13 (62%)