Protein Alignment Rdl and gabra2b

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_073778567.1
• Gene: gabra2b / 100001259
• ZFINID: ZDB-GENE-171102-1
• Length: 451
• Species: Danio rerio
• Alignment Length: 566
• Identity: 159/566 - (28%)
• Similarity: 237/566 - (41%)
• Gaps: 141/566 - (24%)

  Fly    38 HKRIHTVQAATGGGSMLGDVNI-SAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVK 101
            |.|..:..|.|  .:...::.: :.|||.....||.|:||..|.....|...:||.|...:|:..
Zfish    19 HTRSVSADATT--DAFKNNITLFTRILDRLLDGYDNRLRPGLGDRVTTVKTDIYVTSFGPVSDTD 81

  Fly   102 MDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIR 166
            |::|:|.:|||.|.|.||.:.....:  |.:.:.....||.|||||.|.|:|..|..|..|:.:|
Zfish    82 MEYTIDVFFRQSWKDERLKFEGPMNI--LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLR 144

  Fly   167 VHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFW-RDGLSSVGMSSE- 229
            :...|::..::|||:.|.|||:|:.||||...|.::..|:.||..::.|.| ::..:||.:..|
Zfish   145 IQDDGTLLYTMRLTVHAECPMHLEDFPMDFHSCPLKFGSYAYTTTEVTYTWTKNASNSVVVEEES 209

  Fly   230 VELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRN 294
            ..|.|:.:||.......|..:||.|:.:.......|.:||::||.|:|..:.||:|.|||||||.
Zfish   210 SRLNQYDLLGQTVGNETIRSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 274

  Fly   295 ATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQ 359
            :.|||...|||||||||||..|...:|||::|..::|.::..|:..||::|:|:|||.|..|
Zfish   275 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK--- 336

  Fly   360 MRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMG 424
             |...:.....:.::||::.....:..|.....||..
Zfish   337 -RGWAWDGKSVVNDKKKEKASVIKKNNAYAVAVANYA---------------------------- 372

  Fly   425 PEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSK 489
                            |:..|.||.                      |..             :|
Zfish   373 ----------------PNITKDTVL----------------------PTI-------------AK 386

  Fly   490 GGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKV 554
            |...|.                                 |..:..|.|..|             .
Zfish   387 GSVAEQ---------------------------------GKTKVDGKPAEA-------------K 405

  Fly   555 KDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVAD 600
            |..|.:     |.||:.|||:|||.|..|||:||..||:...|:.|
Zfish   406 KTFNSV-----SKIDRMSRIMFPVLFGSFNLVYWATYLNREPVIKD 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	60/184 (33%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	75/313 (24%)
gabra2b	XP_073778567.1	None