DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5280 and 1700088E04Rik

DIOPT Version :9

Sequence 1:	NP_648278.1	Gene:	CG5280 / 39033	FlyBaseID:	FBgn0035952	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_613047.1	Gene:	1700088E04Rik / 27660	MGIID:	1920774	Length:	216	Species:	Mus musculus

Alignment Length:	212	Identity:	63/212 - (29%)
Similarity:	109/212 - (51%)	Gaps:	20/212 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MWPSERIPPGGAG-AFHSAKVQ--YSKETADLIRLLVKESKMSMLVRKQIDESLRNGEPLPLPEP 99
            |...||:.....| .|...:.|  |:..|.:|:|:::||||::...::.|.::::.|.||||...
Mouse     1 MASQERVDSVTKGTGFRRCRKQAGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCN 65

  Fly   100 PRPNTNNDPDKETLA------ILDRARNAKRKNLRQ---IEASGAYKQSYYRPPADNRMHGEKAK 155
            |..:....|.|:..:      ||     |...:||.   .:|:|||.:..::|.|...:  ||.|
Mouse    66 PTSSLRGSPSKKAASAIYLPPIL-----ATHSHLRPASLCQANGAYSREQFKPQATRDL--EKEK 123

  Fly   156 SQLQFTMAGTHLPDPAIKPRRRPREEQLVTEEDLINELLDQINERAEWLTEMESMGQGKKYRPEI 220
            .:||...| |.......|.....|:|....|.|..:||:.:|.:|.|:|..||::|||::||..|
Mouse   124 RRLQNIFA-TGKDKEERKKVPHVRQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSII 187

  Fly   221 RDQIAERLRRIQALESK 237
            ..:|:::||.::.::.:
Mouse   188 LAEISQKLREMEDIDRR 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5280	NP_648278.1	UPF0193	40..241	CDD:283026	62/210 (30%)
1700088E04Rik	NP_613047.1	UPF0193	6..211	CDD:283026	61/207 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850497
Domainoid	1	1.000	86	1.000	Domainoid score	I8125
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5151
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52348
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007385
OrthoInspector	1	1.000	-	-		oto94481
orthoMCL	1	0.900	-	-		OOG6_106698
Panther	1	1.100	-	-	LDO	PTHR28348
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4558
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.890