Protein Alignment CG5653 and SMOX

DIOPT Version :10

• Sequence 1: NP_648269.1
• Gene: CG5653 / 39024
• FlyBaseID: FBgn0035943
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001257620.1
• Gene: SMOX / 54498
• HGNCID: 15862
• Length: 585
• Species: Homo sapiens
• Alignment Length: 592
• Identity: 167/592 - (28%)
• Similarity: 243/592 - (41%)
• Gaps: 163/592 - (27%)

  Fly     5 RASSRIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDNVIDLGAQWCHGKQQ 69
            |...|:::||||::|:|||..||:..|.:|.:|||...||||:.:|..|....:|||.|.||...
Human    22 RGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSHG 86

  Fly    70 NCVYDMVKDMGILHETGDYYSPIKRVRSNKEVVPHELACRI--HDIAVKSMPSGPHPVVGSFGT- 131
            |.:|.:.:..|:|.||.|....:.|:....:   :.:||.:  |...:      |..||..|..
Human    87 NPIYHLAEANGLLEETTDGERSVGRISLYSK---NGVACYLTNHGRRI------PKDVVEEFSDL 142

  Fly   132 -----HLTQTFWR-------------------------KIESELPQVNRDVASEALNTFAKHESS 166
                 :|||.|:|                         :.:.:.|:..:.:....:..:.|.||.
Human   143 YNEVYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQYLKVESC 207

  Fly   167 IIGADNLFEVSVREHIEYHECDGDKLLHWGTKGYRRFLRLLMKVSADTPEELGLLEGRIQLDMKV 231
            ...:.::.|||:....|:.|..|..  |....|:.|.:.||.:         |:....|||...|
Human   208 ESSSHSMDEVSLSAFGEWTEIPGAH--HIIPSGFMRVVELLAE---------GIPAHVIQLGKPV 261

  Fly   232 IKIE----LACPR-------------------------------------KVILRCQDGDYFEAD 255
            ..|.    .|.||                                     .|::.|:|.:...||
Human   262 RCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEPRGGRWDEDEQWSVVVECEDCELIPAD 326

  Fly   256 HVICTVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEYEKQPLPDGWVGFFCFW--- 317
            |||.|||||||:.|:...|.|.||..||.||..|.:||.:|::||:|:.           ||
Human   327 HVIVTVSLGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEP-----------FWGPE 380

  Fly   318 ------LEEDLIELRKTEY---FWVEGITGVHMITCQPR---MLMAWVNGPHGRHMETLSDEKVL 370
                  :.||..|.....|   .|...|.|..::....|   :|..|:.|.....||...||.|.
Human   381 CNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVA 445

  Fly   371 EGLYWLFRKFL-TFEIPPPKRFVRSSWFSNPNFRGSWSYRGVMADERNTGPWDLE---------- 424
            |....:.|:|. ...||.|:|.:||:|.|||.||||:||..|     .:...|:|
Human   446 EICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQV-----GSSGADVEKLAKPLPYTE 505

  Fly   425 -------SPVLGEDGHL--------------------GLLFAGEASSRNHFSTVHGAVEAGYREA 462
                   |....:.|||                    .:||:|||:.|.::||.|||:.:|.|||
Human   506 SSKTAHGSSTKQQPGHLFSSKCPEQPLDANRGAVKPMQVLFSGEATHRKYYSTTHGALLSGQREA 570

  Fly   463 DRLIDHY 469
            .|||:.|
Human   571 ARLIEMY 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:396255	158/575 (27%)
SMOX	NP_001257620.1	PLN02568	50..578	CDD:215308	154/564 (27%)