DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5653 and CG8032

DIOPT Version :9

Sequence 1:	NP_648269.1	Gene:	CG5653 / 39024	FlyBaseID:	FBgn0035943	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001262380.1	Gene:	CG8032 / 41026	FlyBaseID:	FBgn0037606	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	148/545 - (27%)
Similarity:	226/545 - (41%)	Gaps:	116/545 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDN-VIDLGAQWCHGKQQNCV 72
            :|:|||||::|::||..||||...:..||||..|:||||.::...:| .|:|||.|.||...|.:
  Fly    41 KIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELGANWIHGVLGNPI 105

  Fly    73 YDMVKDMGILHETGDYYSPIKRVRSNKE--VVPHELACRIHDIAVKSM---------PSGPHPVV 126
            :::....|:: ...:...|.|.|.:.::  .||..:...|::..|..:         ...|.|.:
  Fly   106 FELAVQHGLV-SVVNVPKPHKVVATTEDGHQVPFNILQEIYEAYVCFLRRCDEYFLCQYSPPPDI 169

  Fly   127 GSFGTHLTQTFWRKIESELPQV----NRDVASEALNTFAKHESSIIGADNLFEVSVREHIEYHEC 187
            .|.|.|:..    :||..|..|    .:.:.....|...|.|:.|.|.:|:.||.:.|...|.|.
  Fly   170 HSVGEHINY----EIEIYLSGVQDPKEKRLKQSIFNCLLKRETCITGCNNMDEVDLLELGSYTEL 230

  Fly   188 DGD------------------------------KLLHWGTKGYRRFLRLL--------------- 207
            .|.                              |.:||..|  :.|..|.
  Fly   231 QGGNIVLPTGYSSILRPLGAQIAKQSILTKCPVKKIHWKRK--KTFTGLETVDENSEDEHSDDSE 293

  Fly   208 -------------MKVSADTPEELGLLEGRIQLDMKVIKIELACPRKVILRCQDGDYFEADHVIC 259
                         ..|.::|........|.:::|                 |:||..|.|.||||
  Fly   294 RTVTEVPTGEIRGASVESNTSSNCDYPAGNVRID-----------------CEDGRVFHAAHVIC 341

  Fly   260 TVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEYEKQPLPDGWVGFFCFWLEEDLIE 324
            |:.||||:..|..||.|.||..|..:|.:|..|||:|::||||:..|..........| ::|..:
  Fly   342 TIPLGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERPFLSADISEIMLLW-DDDKRD 405

  Fly   325 LRKTE-------YF---WVEGITGVHMITCQPRMLMAWVNGPHGRHMETLSDEKVLEGLYWLFRK 379
            :..:|       |.   |.:.|.....:|  ..:|:.||:|....:||.|..|.|.|....:.|.
  Fly   406 MNSSEEELASEAYLSKNWFKKIYSFAKVT--DTLLLGWVSGREAEYMEKLDHEAVAEKCTEILRN 468

  Fly   380 FLTFE-IPPPKRFVRSSWFSNPNFRGSWSYRGVMADERNTGPWDLESPVLGEDGHL--GLLFAGE 441
            ||... :|.|||.|.:||.|. :|.|. :|..:..........:|..|:......:  .::||||
  Fly   469 FLQDPYVPKPKRCVCTSWKSQ-DFTGG-AYTSIPVGATQEDIENLAQPLYATPQAMKPAIVFAGE 531

  Fly   442 ASSRNHFSTVHGAVEAGYREADRLI 466
            .:..:.:||||||..:|...|..|:
  Fly   532 HTHSSFYSTVHGAYLSGRTAAQHLL 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	30/66 (45%)
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:279874	141/535 (26%)
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	29/59 (49%)
CG8032	NP_001262380.1	Amino_oxidase	49..556	CDD:279874	141/535 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452803
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	1	1.000	-	-		otm46708
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	1	1.100	-	-	P	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
	9	8.750