DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5653 and Su(var)3-3

DIOPT Version :10

Sequence 1:NP_648269.1 Gene:CG5653 / 39024 FlyBaseID:FBgn0035943 Length:476 Species:Drosophila melanogaster
Sequence 2:NP_649194.1 Gene:Su(var)3-3 / 40217 FlyBaseID:FBgn0260397 Length:890 Species:Drosophila melanogaster


Alignment Length:611 Identity:146/611 - (23%)
Similarity:242/611 - (39%) Gaps:198/611 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 RIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDNVIDLGAQWCHGKQQNCVY 73
            ::|:||||:||:|.|.:|.|.. .:|.:|||.||:||||:|......:.|:||....|...|.:.
  Fly   266 KVIVIGAGISGLAVAHQLQQFG-MDVIVLEARDRVGGRISTFRKNSYIADVGAMVVTGVYGNPMT 329

  Fly    74 DMVKDMGI----LHETGDYYSP----------------IKRVRSNKEVVPHEL------ACRIH- 111
            .:.|.:|:    :.:|...|.|                ..|:..:...:.|.|      .|.:. 
  Fly   330 ILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLESASYLSHRLDFNYAGDCPVSL 394

  Fly   112 ------DIAVKSMPSGPHPVVGSFGTHL-----TQTFWRKIESELPQVN--RDVASEALNTFAKH 163
                  .|:::.|     .|:...|.|:     |||   ||..:..::.  ||...:..|   :|
  Fly   395 GDALEWIISMQEM-----QVMHKRGQHMQEIIATQT---KIIEQRRRLKTLRDTIGKLKN---EH 448

  Fly   164 ESSI-----IGAD----------NL--FEVSVREHIE-YHECDGDKLLHWGTKGYRRFLRLLMKV 210
            .:.|     .|.|          |:  .::.:.|.|. :|:...::         ::.|..|.::
  Fly   449 LAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEE---------KQMLAKLHEL 504

  Fly   211 SADTPEELGL-LEGRIQLDMKVIKIELACPRK---VILR--CQDGDY------------------ 251
            ..:.|.::.| ...|:.||.....:|.|...:   :.|:  .||.|:                  
  Fly   505 EQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVPV 569

  Fly   252 ---------------------------------------FEADHVICTVSLGVL---------QE 268
                                                   ::||.|:||::||||         |:
  Fly   570 ALTENLDIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLGVLKVAVAHKESQQ 634

  Fly   269 QHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEYEK---QPLPD--GWVG--------FFCFWLEE 320
            .:...|.||||..|..||:.|..|.:||:.|.:::   .|..:  |.||        .|.||   
  Fly   635 SNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVGSTTASRGEMFLFW--- 696

  Fly   321 DLIELRKTEYFWVEGITGVHMITCQPRMLMAWVNGPHGRHMETLSDEKVLEGLYWLFRK-FLTFE 384
                                .|:..| :|:|.|.|.....:|:::|:.::.....:.:. |....
  Fly   697 --------------------SISSSP-VLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTS 740

  Fly   385 IPPPKRFVRSSWFSNPNFRGSWSYRGVMADERNTGPWD-LESPVL-----GEDGHLGLLFAGEAS 443
            :|.||..|.:.|.|:|..|||:||..|.:   :...:| |.:||:     ..:|...|.||||.:
  Fly   741 VPQPKETVVTRWRSDPWARGSYSYVSVGS---SGSDYDLLAAPVIPPSSKDAEGLPRLFFAGEHT 802

  Fly   444 SRNHFSTVHGAVEAGYREADRLIDHY 469
            .||:.:|||||..:|.|||.|:.|:|
  Fly   803 IRNYPATVHGAYLSGLREAGRIADYY 828

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5653NP_648269.1 Amino_oxidase 17..466 CDD:396255 139/598 (23%)
Su(var)3-3NP_649194.1 PLN03000 74..>827 CDD:178578 144/608 (24%)

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