DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5653 and Paox

DIOPT Version :9

Sequence 1:	NP_648269.1	Gene:	CG5653 / 39024	FlyBaseID:	FBgn0035943	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001099781.1	Gene:	Paox / 293589	RGDID:	1561125	Length:	531	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	147/482 - (30%)
Similarity:	214/482 - (44%)	Gaps:	108/482 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VIDLGAQWCHGKQQ-NCVYDMVKDMGILHETGDYYSPIKRVRSNKEVVPHELACRIHDIAVKSMP 119
            |::|||.|.||..| |.|:.:..:.|:|.|        |.:....::|  |....:...:|....
  Rat    83 VVELGAHWIHGPSQGNPVFQLAAEFGLLGE--------KELSEENQLV--ETGGHVALPSVSCTS 137

  Fly   120 SGPHPVVGSFGTHLTQTFWRKI--------ESELP----------QVNRDVAS------------ 154
            ||. .|.....|.:...|:..|        |||.|          ::::.||:
  Rat   138 SGT-SVSLELVTEMGSLFYGLIDRTREFLNESETPMASVGEFLKKEISQQVANWTEDENTKRLKL 201

  Fly   155 EALNTFAKHESSIIGADNLFEVSVREHIEYHECDG-DKLLHWGTKGYRRFLRLLMKVSADTPEEL 218
            ..||||...|..:.|..::..|::....||....| |..|..|.:|      |...:.|..|:|:
  Rat   202 AVLNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCTLSGGYQG------LTNCILASLPKEV 260

  Fly   219 GLLEGRIQLDMKVIKI--------ELACPRK---VILRCQDGDYFEADHVICTVSLGVLQEQHEK 272
            .:.:       |.:|.        |.|.|.:   |::.|:||....|.|||.||.||.|:|..:.
  Rat   261 MVFD-------KPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDT 318

  Fly   273 LFVPPLPAAKVNAIRSLTLGTVNKLYLEYEKQPLPDGWVGFFCFW----------------LEED 321
            .|.|||||.|..|||.|..||.||::||:|:.           ||                |::.
  Rat   319 FFEPPLPAKKAEAIRKLGFGTNNKIFLEFEEP-----------FWEPDCQFIQVVWEDTSPLQDS 372

  Fly   322 LIELRKTEYFWVEGITGVHMITC--QPRMLMAWVNGPHGRHMETLSDEKVLEGLYWLFRKFL-TF 383
            .:.|:.|   |.:.:.|..::..  ...:|.|::.|.....|||||||:||..|..:.|:.. ..
  Rat   373 PLSLQDT---WFKKLIGFLVLPSFESSHVLCAFIAGLQSEFMETLSDEEVLLSLTQVLRRVTGNP 434

  Fly   384 EIPPPKRFVRSSWFSNPNFRGSWSYRGVMADERNTG-PWDLESPVLGEDG---HLGLLFAGEASS 444
            ::|..|..:||.|.|.|..|||:||..|    .:|| ..||.:..|..||   .|.:||||||:.
  Rat   435 QLPAAKSVLRSRWHSAPYTRGSYSYVAV----GSTGDDLDLMAQPLPADGTGTQLQVLFAGEATH 495

  Fly   445 RNHFSTVHGAVEAGYREADRLIDHYTS 471
            |..:||.|||:.:|:|||||||..:.|
  Rat   496 RTFYSTTHGALLSGWREADRLIGLWDS 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	10/22 (45%)
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:279874	144/475 (30%)
Paox	NP_001099781.1	Amino_oxidase	77..517	CDD:279874	144/475 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.650