Protein Alignment GstO1 and GSTT2B

DIOPT Version :10

• Sequence 1: NP_648237.1
• Gene: GstO1 / 38975
• FlyBaseID: FBgn0035907
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001074312.1
• Gene: GSTT2B / 653689
• HGNCID: 33437
• Length: 244
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 54/217 - (24%)
• Similarity: 75/217 - (34%)
• Gaps: 69/217 - (31%)

  Fly    36 VHLVLDAKKIPYHAIYI---------NLR--------DKPEWFSLVSSSTKVPALELVKEQGNPV 83
            :.|.||....|..|:||         .||        .|.:.|..::|..|:|.|    :.|:.:
Human     3 LELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTL----KDGDFI 63

  Fly    84 LIESLIICDYLDEKYPEVP--LYPKDLLKKAQEKILIERFGQFINAFYYLLLHDN--------PE 138
            |.||..|..||..|| :.|  .||.||..:|:             ...||..|.:        |.
Human    64 LTESSAILIYLSCKY-QTPDHWYPSDLQARAR-------------VHEYLGWHADCIRGTFGIPL 114

  Fly   139 QLVDTDHYAGLVVYEEELKRRCT-----------KFFG------GDSPGMLDYMMWPWCERFDSL 186
            .:.......|:.|.||:::|..|           ||.|      |....:.|.|      ..:.|
Human   115 WVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLM------ALEEL 173

  Fly   187 KYTFEQKFELSPERFPTLIKWR 208
            .......:||...| |.|..||
Human   174 MQPVALGYELFEGR-PRLAAWR 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO1	NP_648237.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	21/75 (28%)
		GST_C_Omega	109..234	CDD:198293	25/125 (20%)
GSTT2B	NP_001074312.1	GST_N_Theta	3..78	CDD:239348	22/78 (28%)
		GST_C_Theta	91..216	CDD:198292	25/124 (20%)