Protein Alignment GstO3 and GSTO1

DIOPT Version :10

• Sequence 1: NP_648234.1
• Gene: GstO3 / 38972
• FlyBaseID: FBgn0035904
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_004823.1
• Gene: GSTO1 / 9446
• HGNCID: 13312
• Length: 241
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 91/234 - (38%)
• Similarity: 125/234 - (53%)
• Gaps: 23/234 - (9%)

  Fly     3 SGKHLAKGSPKPVLPDDGVLRLYSMRFCPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEVSPL 67
            |.:.|.|||..|....:|.:|:|||||||:|:|..|||.||.:.:..:.|||..||||..:.:|.
Human     5 SARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPF 69

  Fly    68 LKVPALQLVAEKGEPSLI-ESLIIAEYLDDKYPENPLLPKDPLKRAQDKILLERFSSITSAFINI 131
            ..||.|    |..:..|| ||.|..||||:.||...|||.||.::|..|::||.||.:.| .:..
Human    70 GLVPVL----ENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPS-LVGS 129

  Fly   132 LVQGTGLEDYWTALDIF-------EEELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELKLQKE 189
            .::....|||....:.|       ||.||.:.|.:||||....:||:||||||||..::|
Human   130 FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKL----- 189

  Fly   190 YNFNE--SRFPKITKWIALLKADSVVQSFYATPEQHNEF 226
               ||  ...||:..|:|.:|.|..|.:...:.:....|
Human   190 ---NECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGF 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO3	NP_648234.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	41/92 (45%)
		GST_C_Omega	109..230	CDD:198293	41/127 (32%)
GSTO1	NP_004823.1	GST_N_Omega	5..94	CDD:239353	41/92 (45%)
		GST_C_Omega	108..229	CDD:198293	41/127 (32%)