Protein Alignment GstO3 and CLIC6

DIOPT Version :10

• Sequence 1: NP_648234.1
• Gene: GstO3 / 38972
• FlyBaseID: FBgn0035904
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_001303938.1
• Gene: CLIC6 / 54102
• HGNCID: 2065
• Length: 704
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 42/189 - (22%)
• Similarity: 82/189 - (43%)
• Gaps: 32/189 - (16%)

  Fly    30 CPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEVSPLLKVPALQLVAE-KGEPSLIESLIIAEY 93
            ||::||..::|..|.|.::...::|..||..|..::|....|.:....| |.:.:.||..:..:.
Human   487 CPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKL 551

  Fly    94 LDDKYPENPLLPKDPLKRAQDKILLERFSSITSAFI-------------NILVQGTGLEDYWTA- 144
            ...:||:  |..:.|...:....:..:|    ||||             |:|.....|::|..:
Human   552 APPRYPK--LGTQHPESNSAGNDVFAKF----SAFIKNTKKDANEIHEKNLLKALRKLDNYLNSP 610

  Fly   145 ----LDIFE-EELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELKLQKEYNFNESRFP 198
                :|.:. |::|..|..:..|::....|..:.|   :|.:|::..:|   :.:..||
Human   611 LPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLP---KLHIIKIVAKK---YRDFEFP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO3	NP_648234.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	17/65 (26%)
		GST_C_Omega	109..230	CDD:198293	21/109 (19%)
CLIC6	NP_001303938.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..446
		PRK07764	<9..382	CDD:236090
		13 X 10 AA tandem repeat of G-D-[SNG]-[VIM]-[DEQ]-A-[EAG]-[GDVE]-[PRG]-[LAVP]	157..282
		O-ClC	471..704	CDD:129941	42/189 (22%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Y696	487..490		2/2 (100%)