Protein Alignment Exo70 and Exoc7

DIOPT Version :10

• Sequence 1: NP_648222.3
• Gene: Exo70 / 38959
• FlyBaseID: FBgn0266667
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_001349767.1
• Gene: Exoc7 / 53413
• MGIID: 1859270
• Length: 720
• Species: Mus musculus
• Alignment Length: 731
• Identity: 244/731 - (33%)
• Similarity: 388/731 - (53%)
• Gaps: 69/731 - (9%)

  Fly     9 QAHNKLEKEATNLALLKDRVDKYHDLSTQMSSILTIFEKRLGNLEQTILPVYQETEQLQKRQQNL 73
            :..:||::|...|:.::|.::|...|:..|.|||:.||.||..||.:|:||:::||.||:.|:|:
Mouse    13 EIEDKLKQEEETLSFIRDSLEKSDQLTRNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENV 77

  Fly    74 EATLNCLESVLSHYDVSQEVCQLIHQGPVEGNISVFLDALAKLRDANDYFRHNNSQSVELENVTS 138
            |.||:||:.|:|:|.|:.:..::|.:||. |.:..:|.::||::.|.:||:.|:..|.||..|..
Mouse    78 EKTLSCLDHVISYYHVASDTEKIIREGPT-GRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKL 141

  Fly   139 LFNTGCEGLSQHYSMLLKKHSAPLKPVELLDLIYIEDD-SSDEYTSFRQLSQTTREELYTISHWL 202
            ||..|.|.|...:..|:.:||..:.||.|||||..:|: ...|......|.::...::..||.||
Mouse   142 LFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEVQEDVVLEHLPESVLRDVVRISRWL 206

  Fly   203 EQNLR--EYTNIYATERGEVVLRSLQLLKDH-QKSNSWGHEALRPR-HSGRQTEPKKTTSARLQQ 263
            .:..|  ::.|:|...|...:.||::.||:| :||:|.......|. .:.|:..|.|....|...
Mouse   207 VEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGT 271

  Fly   264 IFEKKANKLYLRATQTIEQSTGFSIKKASSH------------SDHLTSEDLMDG---------- 306
            |  :||..|..:.:|     .|...||..|:            ..|| ||.|.|.
Mouse   272 I--RKAQNLLKQYSQ-----HGLDGKKGGSNLIPLEGHEHDFRVKHL-SEALNDKRGPLAGRDDM 328

  Fly   307 -DQELDKYLVMLLGLQRLLNWERAIMIDIIPQSKHNEVFATLAYNAIDLVVKDAEAITQRILRCI 370
             |.|.|.|:..:....:|...|..::::|||:....:.|.:|..:|:|.::.:.|.|.....:.|
Mouse   329 LDVETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAI 393

  Fly   371 SRKEWTSALGIFSALKRVILLQPDIDRTYD---PAQREQLKKVLKKLQHTGAKALEHFLDVVKGE 432
            .|.::::.|.:|..|:.:...:|:.|:...   .:.:.:|..::..::..||||||.|.|.:|.:
Mouse   394 IRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKND 458

  Fly   433 SSTNIVGQSNVPKDATVHELTSNTIWFIEHLYDHFDVIGSILAQDVL---YSTQLDTILMKKALP 494
            ...    :.|:|||.||||||||.|.|::.|.|..:..|::||..||   |:..||        |
Mouse   459 PDK----EYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQVLGDTYNIPLD--------P 511

  Fly   495 VE----------ERNKALLAIYIKKALAELNLSIMNKCEQYNDQATKHLFRLNNIHYILKSLQRS 549
            .|          |.:|.||:.||.|.|..|.|::::|.:.|.|.|...:|..||.:||||||::|
Mouse   512 RETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKS 576

  Fly   550 NLIDLVTLAEPECEHSYMEMIRELKASYQKTWSKMLVGIYSLDE-LPKPVAG-KVKDKDRSVLKE 612
            .||.||.:.:...|.||.|.|.:...:||::|.|  |..|..:: ||....| |::||:|.::||
Mouse   577 ELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLK--VTDYIAEKNLPVFQPGVKLRDKERQMIKE 639

  Fly   613 RFSNFNKDFEEACKIQRGISIPDVILREGIKRDNVEHILPIYNRFYEIYSGVHFSKNPDKYVKYR 677
            ||..||...||.||||:..:|||...|:.|::...:.:...|..|...|..|.|:|||:||:|||
Mouse   640 RFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYR 704

  Fly   678 QHEINAMLSKLFDDSA 693
            ..::..|:.:|||.||
Mouse   705 VEQVGDMIDRLFDTSA 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exo70	NP_648222.3	Exo70	315..686	CDD:460798	131/388 (34%)
Exoc7	NP_001349767.1	Exo70	336..714	CDD:460798	132/391 (34%)