Protein Alignment Exo70 and Exo70

DIOPT Version :10

• Sequence 1: NP_648222.3
• Gene: Exo70 / 38959
• FlyBaseID: FBgn0266667
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: XP_557360.4
• Gene: Exo70 / 1277272
• VectorBaseID: AGAMI1_006372
• Length: 709
• Species: Anopheles gambiae
• Alignment Length: 708
• Identity: 418/708 - (59%)
• Similarity: 538/708 - (75%)
• Gaps: 16/708 - (2%)

  Fly     1 MNNLDSSLQAHNKLEKEATNLALLKDRVDKYHDLSTQMSSILTIFEKRLGNLEQTILPVYQETEQ 65
            |:.|:::||...|||||.||.|||||.|:||.:|:..||.||..||:|||.||.||||||..|:.
Mosquito     1 MSTLENTLQIEIKLEKEKTNQALLKDHVEKYSELTQSMSKILNSFEQRLGKLEHTILPVYNITKN 65

  Fly    66 LQKRQQNLEATLNCLESVLSHYDVSQEVCQLIHQGPVEGNISVFLDALAKLRDANDYFRHNNSQS 130
            |||:||||::||.|:|.||||||.||:||.||||||.||||..|||.|.||:.|.|||.:||.||
Mosquito    66 LQKQQQNLDSTLQCMEQVLSHYDASQDVCNLIHQGPSEGNIGSFLDGLNKLKKAKDYFLNNNPQS 130

  Fly   131 VELENVTSLFNTGCEGLSQHYSMLLKKHSAPLKPVELLDLIYIEDDSSDE-YTSFRQLSQTTREE 194
            |||||||||||.|||.|:.|:..|||||:||||||:|||:||||:|||:| ..|.:|:..:.|||
Mosquito   131 VELENVTSLFNNGCETLNNHFKSLLKKHNAPLKPVDLLDMIYIEEDSSNEDCPSIKQVPPSAREE 195

  Fly   195 LYTISHWLEQNL-REYTNIYATERGEVVLRSLQLLKDHQKSNSWGHEALRPRHSGRQTEP--KKT 256
            |..::.||:.|| |||..|:..||.||::||||.|||||||.|||:|.||.||...:.|.  |||
Mosquito   196 LNVMAQWLDNNLRREYVQIFGDERSEVIMRSLQNLKDHQKSGSWGNEPLRTRHGYGRAEAGVKKT 260

  Fly   257 TSARLQQIFEKKANKLYLRATQTIEQSTGFSIKKASSHSDHLTSEDL-MDGDQELDKYLVMLLGL 320
            ||||||||||:||||::::|:||:.||.|.:::|.||..|.|.:|:. .|.||||:||||:||||
Mosquito   261 TSARLQQIFERKANKMFMKASQTLGQSAGLAMRKNSSFGDILAAEEYGNDNDQELEKYLVLLLGL 325

  Fly   321 QRLLNWERAIMIDIIPQSKHNEVFATLAYNAIDLVVKDAEAITQRILRCISRKEWTSALGIFSAL 385
            |:||.|||.::.||:|.|:|||||:.|:..:|::||||||.||.:::|.|.||||::||||||||
Mosquito   326 QKLLVWERQLLNDIVPPSRHNEVFSRLSQPSIEMVVKDAEQITSKVMRSIGRKEWSAALGIFSAL 390

  Fly   386 KRVILLQPDIDRTYDPAQREQLKKVLKKLQHTGAKALEHFLDVVKGE-----------SSTNIVG 439
            |.|.:|||||||..|..|::||..||.:||.|.:||||.|::.|:.:           |:.:..|
Mosquito   391 KHVQILQPDIDRICDSTQKQQLSGVLNRLQQTASKALEQFIESVRNDAGGGGMVSMTSSTISYGG 455

  Fly   440 QSNVPKDATVHELTSNTIWFIEHLYDHFDVIGSILAQDVLYSTQLDTILMKKALPVEERNKALLA 504
            .|:||:||||:|||||||||:|.|.:|.|.||.:|..:.:|:..||.|..:|||.:|::|||||.
Mosquito   456 GSSVPRDATVYELTSNTIWFLEQLQEHCDTIGGLLQTEAIYTNDLDRIASQKALTMEQKNKALLG 520

  Fly   505 IYIKKALAELNLSIMNKCEQYNDQATKHLFRLNNIHYILKSLQRSNLIDLVTLAEPECEHSYMEM 569
            ||::|.|||||.:|..|.|||:|.|||.||:|||.||||||||||:||::|.|.|.:||..|.:|
Mosquito   521 IYVRKVLAELNYTIATKSEQYSDTATKQLFKLNNTHYILKSLQRSSLIEIVALTEHDCERRYQKM 585

  Fly   570 IRELKASYQKTWSKMLVGIYSLDELPKPVAGKVKDKDRSVLKERFSNFNKDFEEACKIQRGISIP 634
            |::||.:|..:|||||..|:.||::|:|:.||||||:|:.:|:||.||||:.:||.||||.||:|
Mosquito   586 IQDLKKAYLGSWSKMLSFIHPLDDMPRPINGKVKDKERATIKDRFFNFNKELDEAVKIQRAISVP 650

  Fly   635 DVILREGIKRDNVEHILPIYNRFYEIYSGVHFSKNPDKYVKYRQHEINAMLSKLFDDS 692
            ||:|||||||||.|||:|.||.|:|.||.|.||||.|||||||..::..||:..|||:
Mosquito   651 DVLLREGIKRDNTEHIVPKYNAFFEGYSDVQFSKNIDKYVKYRPSDVTTMLNSFFDDT 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exo70	NP_648222.3	Exo70	315..686	CDD:460798	218/381 (57%)
Exo70	XP_557360.4	None