DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sbp2 and Secisbp2l

DIOPT Version :9

Sequence 1:	NP_648204.1	Gene:	Sbp2 / 38934	FlyBaseID:	FBgn0087039	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_808276.2	Gene:	Secisbp2l / 70354	MGIID:	1917604	Length:	1089	Species:	Mus musculus

Alignment Length:	355	Identity:	94/355 - (26%)
Similarity:	152/355 - (42%)	Gaps:	62/355 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KITPRSSKYKNQHRKREQQTSLLDFVIKPRPKTQRQTKAHKLQKT----HLAIT----------R 69
            |:....||...:..|...|..|.| ::....|.|:..||.::..|    |..:|          |
Mouse   470 KLQEALSKAAGKKTKTPVQLDLGD-MLAALEKQQQAMKARQITNTRPLAHPVVTTATFHTKDSNR 533

  Fly    70 GSYIVYKP----------------KGKTRLDPK-KKITRLKKSVRVYRTSKKAEREVAE------ 111
            .:....:|                |||.:...| |:.|.|||.:...|..||. |.:.|
Mouse   534 KTLAKSQPCVTSFNSLDITSSKAKKGKEKEIAKLKRPTALKKVILKEREEKKG-RLIVEHSVLGA 597

  Fly   112 -----------NDLEGVPVVGQDIN---PNAIPLEQQVQNLSLSKTPAP---------NNPSQAK 153
                       |||....|..:|..   |:...|....||.....||..         .:|..:.
Mouse   598 EEPTETHLDLTNDLPQETVSQEDAGLSMPSDASLSPASQNSPYCMTPVSQGSPASSGIGSPMASS 662

  Fly   154 TVHAIHSRRFRSYCDNCTRPRLKELSTQLLRDLDRFQKRAFAKNEIKARAHPRLVLGVREALARL 218
            |:..|||:|||.||:......:.|..|.||::|..||:|.:.|:.::|:|..|||:|:||....:
Mouse   663 TITKIHSKRFREYCNQVLSKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHM 727

  Fly   219 RINKVKLLFLATDCEICPGESGLDATIEGLKFQCQQQQVPYCFPLLRRELSYALQKRAQICCVAI 283
            ::||:|.:.::.:||....:.|||..:..:....::|::|:.|.|.|:.|...:.|...:..|.|
Mouse   728 KLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGI 792

  Fly   284 LDFDGANATYADLLNEIEDARAEYKRRTAS 313
            .::.||.:.:..|:...|:||..||...|:
Mouse   793 FNYFGAESLFNRLVELTEEARKAYKDMVAA 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sbp2	NP_648204.1	Ribosomal_L7Ae	200..290	CDD:279573	26/89 (29%)
Secisbp2l	NP_808276.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..207
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..386
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	618..660		8/41 (20%)
		Ribosomal_L7Ae	700..802	CDD:279573	29/101 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	883..907
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	922..1089
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845786
Domainoid	1	1.000	66	1.000	Domainoid score	I9896
eggNOG	1	0.900	-	-		E1_28N3Y
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43423
orthoMCL	1	0.900	-	-		OOG6_105656
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5622
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.670