DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sbp2 and AgaP_AGAP002276

DIOPT Version :9

Sequence 1:	NP_648204.1	Gene:	Sbp2 / 38934	FlyBaseID:	FBgn0087039	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	XP_307904.5	Gene:	AgaP_AGAP002276 / 1269283	VectorBaseID:	AGAP002276	Length:	441	Species:	Anopheles gambiae

Alignment Length:	397	Identity:	108/397 - (27%)
Similarity:	170/397 - (42%)	Gaps:	111/397 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EKI--RRSRNQDVQDTAIKITPRSSKYKNQHRK----REQQTSLLD--FVIK----------PRP 49
            ||:  |::|.:     |.:...::.||:.|.:|    :.|:..::|  |:.|          |..
Mosquito    55 EKLSARKARKE-----AERQKKQAKKYEEQLKKIRGPKSQKLQIIDESFLEKYRHVQSLPPGPTL 114

  Fly    50 KTQRQTKAHKLQKTHLAITR--------GSYIVYKP--------------KGKTRLDPK-KKITR 91
            ||::::|........:.::.        |..:..||              |||.|..|| ||:||
Mosquito   115 KTKKRSKKAPTDVVQINLSECIREQLAGGERMEPKPIVPIVPQQPLLLLHKGKQREVPKEKKLTR 179

  Fly    92 LKKSVRVYRTSKKAEREVAENDLEGVPVVGQDINPNA------IPLE------------------ 132
            |||.:...||.|            |.|..||....||      :|.|
Mosquito   180 LKKDIIRSRTEK------------GAPGDGQQSAGNAGGAQQPVPAEGGKGANGGLLKSSEATSP 232

  Fly   133 -----------QQVQNLSLSKTPAPNNPSQ---------------AKTVHAIHSRRFRSYCDNCT 171
                       :.::...::..|.|:..|.               ::.....|||.||.|||:..
Mosquito   233 SGGGAVDSPFLKAIERCCINDGPPPSRDSSEYQNGFPSLRVSAAVSRPTALRHSRNFRPYCDHFI 297

  Fly   172 RPRLKELSTQLLRDLDRFQKRAFAKNEIKARAHPRLVLGVREALARLRINKVKLLFLATDCEICP 236
            ...|:||:..::..|..||.:|:|||.|||.|:.|.|:|..|.|..|.:.||:|:.:|.|.|  |
Mosquito   298 SDELRELAEDVVVKLFSFQSKAYAKNPIKAVANKRFVVGFNEVLKLLELRKVRLVLIAPDLE--P 360

  Fly   237 GESGLDATIEGLKFQCQQQQVPYCFPLLRRELSYALQKRAQICCVAILDFDGANATYADLLNEIE 301
            .|: :|..:..:|..|:|.||||.|.|.||::.:.|.|:|.|.||.:|.:.|.:.|...:|:.:|
Mosquito   361 NET-IDQMVANVKMLCRQSQVPYLFALKRRKIGFHLLKKAPISCVGVLSYAGCDDTVKQMLSVVE 424

  Fly   302 DARAEYK 308
            ..|..|:
Mosquito   425 QERESYR 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sbp2	NP_648204.1	Ribosomal_L7Ae	200..290	CDD:279573	37/89 (42%)
AgaP_AGAP002276	XP_307904.5	Ribosomal_L7Ae	326..407	CDD:279573	35/83 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I16794
eggNOG	1	0.900	-	-		E1_28N3Y
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H138200
Inparanoid	1	1.050	123	1.000	Inparanoid score	I7103
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007151
OrthoInspector	1	1.000	-	-		oto108626
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6030
TreeFam	1	0.960	-	-
	10	9.820