Protein Alignment ERR and nhr-286

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001041174.1
• Gene: nhr-286 / 4363091
• WormBaseID: WBGene00044699
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 398
• Identity: 98/398 - (24%)
• Similarity: 153/398 - (38%)
• Gaps: 109/398 - (27%)

  Fly   127 CLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPANNECEI-NKRRRKACQACRFQKCLLM 190
            ||||...::..|||...|.||.|||:|.:......||.....||| .:|..:.|:|||.:|||.:
 Worm     8 CLVCKAPSTEPHYGADVCRACAAFFRRRVFSRFPATCDQLGSCEITGEREVRQCKACRMEKCLQI 72

  Fly   191 GMLKEGVRLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTSLCDVKILEVLNSYEPDALSVQTPP 255
            ||     |:..|:..|.|:..:.:.                             :.|.:|.:...
 Worm    73 GM-----RISNVQSKRDKHDNDKLK-----------------------------KKDEVSEKALV 103

  Fly   256 PQVHT-TSITNDEASSSS----GSIKLESSVVTPNGTCIFQNNNNNDPN----------EILSVL 305
            |..:: .||..:|...||    .:::|:|  :..|.|.:.|......|.          |.|:
 Worm   104 PACYSKVSILPNELQCSSTYDYNNMRLKS--LHLNFTEMLQIRKVRFPKRRATKTLHHAEALT-- 164

  Fly   306 SDIYDKELVSVIGWAKQ-IPGFIDLPLNDQMKLL----QVSW--------AEILTLQLTFRSLPF 357
              |:.|::..|:.|... .|.|..:...||.::|    .:.|        |.:|....|:. ||
 Worm   165 --IFRKDVRLVVDWINHTFPEFSRVLEPDQQRILFRNFYMKWTVFEPAYLAVLLGKPDTYH-LP- 225

  Fly   358 NGKLCFATDVWMDEHLAKECGYTEFYYHCVQIAQRMERI-SP-----RR-------------EEY 403
            .|.:.....|:...||.....|:         ...:.|| ||     |:             .|:
 Worm   226 TGDIVDEVGVYYTRHLCTPTSYS---------LDEVSRIFSPYWADFRKTLVDPVIDAKLSIHEF 281

  Fly   404 YLLKALLLANCDILLDDQSS-----LRAFRDTILNSLNDVVYLLRHSSAVSH---QQQLLLLLPS 460
            .||.|:.|  .||.||.||.     .:..|..:...||.|...|..|::..:   ..:.:|||||
 Worm   282 LLLCAICL--FDIGLDYQSDDCIEFCQTIRQELFRELNAVCKQLCSSNSEDYCFRFSKNMLLLPS 344

  Fly   461 LRQADDIL 468
            :::..|:|
 Worm   345 IQRGIDVL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	33/90 (37%)
		NR_LBD	237..493	CDD:472173	65/287 (23%)
nhr-286	NP_001041174.1	ZnF_C4	8..77	CDD:197701	30/73 (41%)
		Hormone_recep	155..349	CDD:459675	49/210 (23%)