Protein Alignment ERR and nhr-281

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_510351.2
• Gene: nhr-281 / 184567
• WormBaseID: WBGene00008884
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 383
• Identity: 99/383 - (25%)
• Similarity: 144/383 - (37%)
• Gaps: 107/383 - (27%)

  Fly   127 CLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPANNEC---EINKRRRK--ACQACRFQK 186
            |::|...|||.||||.||.|||.||:|.|..|:.|.|..|..|   ||...|:|  .||||||:|
 Worm    23 CMICPKKASGRHYGVFSCCACKMFFRRVIVENLFYKCKQNKTCYENEIITGRQKPPKCQACRFKK 87

  Fly   187 CLLMGML----KEGVRLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTSLCDVKI------LEVL 241
            |:.:||:    ||...||               :|...:|       |.|..:|:      .:.:
 Worm    88 CVNLGMMLPPKKEPKNLD---------------SSITALQ-------TFLAALKLRDDHRQTQFM 130

  Fly   242 NSYEPDALSVQ--TPPPQVHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQ--NN--------- 293
            ..|..|..|::  ...|:|.|...|:.:...|........|....|....|.  ||
 Worm   131 QYYSVDDPSLEEIIANPRVVTMRKTSPDVKLSPHEWGFLDSYSRINFFLCFDFINNLSLVDKNII 195

  Fly   294 -NNNDPNEIL------------SVL-----SDIYDKELVSVIGWAKQIPGFIDLPLNDQMKLLQV 340
             |:|....:|            .:|     :|||..|.:.:.....:|...|...|..::..|:|
 Worm   196 FNSNTMRAVLLGAAMNTKCHGVDILRAPDGADIYPDEAIKLFPTDSKILDRIRCSLIGKLIELEV 260

  Fly   341 SWAEILTLQLTFRSLPFNGKLCFATDVWMDEHLAKECGYTE--FYYHCVQIAQRMERIS-PRREE 402
            |..|.|.|.:.|...|     ..:|:  :..|...|....:  |..|.:.:.::....| |.|
 Worm   261 STDEYLLLSMMFFCDP-----SISTE--LSSHAKNELSKHQKIFSSHLLLLCRQNRAFSAPNR-- 316

  Fly   403 YYLLKALLLANCDIL----------------LD-DQSSLRAFRDTIL------NSLND 437
             |:   .||:.|.|:                :| |....|...||.:      |:.||
 Worm   317 -YM---ELLSLCHIINKTNMDLQYVSMMFQFMDPDYKFKRLLSDTFVDAGAYSNNRND 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	41/98 (42%)
		NR_LBD	237..493	CDD:472173	53/264 (20%)
nhr-281	NP_510351.2	ZnF_C4	22..93	CDD:197701	35/69 (51%)
		HOLI	167..330	CDD:214658	37/175 (21%)