Protein Alignment ERR and nhr-163

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_504766.1
• Gene: nhr-163 / 183182
• WormBaseID: WBGene00016368
• Length: 358
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 81/390 - (20%)
• Similarity: 140/390 - (35%)
• Gaps: 105/390 - (26%)

  Fly   124 RRLCLVCGDVASGFHYGVASCEACKAFFKRTIQG-NIEYTCPANNECEINKRRRKACQACRFQKC 187
            |.||||||...|..|||.:.|.||.|||:|.:.. ..|.:|    .|:........|:.||..||
 Worm    11 RMLCLVCGADGSEPHYGGSCCRACAAFFRRYVHSTKQEISC----TCDQRLISSHPCRYCRMLKC 71

  Fly   188 LLMGMLKEGVRLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTSL----CDVKILEVLNSYEPDA 248
            :.:||.|..|:..|        .:|.:.|::....::....:.|:    |:       |.|...|
 Worm    72 MKIGMCKTQVQPPR--------EKNKILNTFPGTTIMISKLSNSIIPKSCN-------NMYRAVA 121

  Fly   249 LSVQTPPPQ----------VHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNNNDPNEILS 303
            ..|.....:          .:.|.||.        .:...::::...|..||.:.:.....:..|
 Worm   122 KWVDFDQRRKELRGDDYFDYNLTQITK--------MVNFNTNLLWKLGESIFSDVSRLSKEDKNS 178

  Fly   304 VLSDIYDK----------------ELVSVIG---WAKQIPGFIDLPLNDQMKLLQVSWAEILTLQ 349
            ::|:.|.|                :..:.||   :.::...|....:....|:..|...::.:
 Worm   179 MISNFYIKWQLLMEPAIDYSAQYEQFKNYIGSNAYYQKCAYFYGSSMQKGNKISDVETVKVFS-- 241

  Fly   350 LTFRSLPFNGKLCFATDVWMDEHLAKECGYTEFYYHCVQIAQRMERISPRREEYYLLKALLL--- 411
                  ||          |            ::||  ...|:.:.:::..:.||..:..|||
 Worm   242 ------PF----------W------------DYYY--ADFAEPVYKMNYDKVEYMAIFLLLLFDG 276

  Fly   412 ANCDILLDDQSSLRAFRDTILNSLNDVVYLLRHSSAVSHQQQLLLLLPSLRQAD----DILRRFW 472
            |..||..|..:.....|..||..||..     .|:....:.:|..::.:||..|    .:..:||
 Worm   277 AYSDISDDGVNLCTNIRKVILRELNSY-----QSNNNCSEVRLADIMETLRLLDKHEEKLHYQFW 336

  Fly   473  472
             Worm   337  336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	32/93 (34%)
		NR_LBD	237..493	CDD:472173	46/272 (17%)
nhr-163	NP_504766.1	ZnF_C4	13..76	CDD:197701	25/66 (38%)
		Hormone_recep	163..324	CDD:459675	35/197 (18%)