Protein Alignment ERR and nhr-139

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_504767.1
• Gene: nhr-139 / 183179
• WormBaseID: WBGene00016365
• Length: 346
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 88/399 - (22%)
• Similarity: 151/399 - (37%)
• Gaps: 94/399 - (23%)

  Fly   127 CLVCGDVASGFHYGVASCEACKAFFKRTIQGN---IEYTC----PANNECEINKRRRKACQACRF 184
            |.|||...:..|:|..||.||.|||:|.:...   ||.||    |:::          .|:.||.
 Worm     3 CKVCGANGAEAHFGGESCRACAAFFRRYVHSQKLVIECTCLHRLPSSH----------PCRHCRM 57

  Fly   185 QKCLLMGMLKEGVRLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTSL----CDVKILEVLNSYE 245
            :||:..||     .:.:|:|.|:|   |.|...|.....:..:..||:    ||..:..|.|..:
 Worm    58 EKCIATGM-----TMCKVQGNREK---NKVRGYYPGYLPVISTLPTSVIPKSCDNILRTVANWVD 114

  Fly   246 PDALSVQTPPPQVHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNNNDPNEILSVLSDIYD 310
            .|....|.........::|.....|     |::|.::...|..||.:.:..:..:..|::::.:.
 Worm   115 LDQTRKQLRGENFFDHNLTQVTKLS-----KMDSKLLWDLGEVIFSDVSKFNSFDKDSMIANFFP 174

  Fly   311 KELVSVIGWAKQIPGFIDLPLNDQMKLLQVSWAEILTLQLTF--RSLPFNGKLCFATDVWMDEHL 373
            |.::....        ||..||.:.....:...|.......|  .|:|...:|       .||..
 Worm   175 KWIIMECA--------IDYSLNQEQFQSFIGSIEYYKKCAHFYGSSMPEEKRL-------DDEDT 224

  Fly   374 AKECGYTEFY-YHCVQIA-----QRMERISPRREEYYLLKALLL---ANCDILLDDQSSLRAFRD 429
            .|.  :::|: :|..:||     ::.::|     ||..:..|||   |..:|..|.....:..|.
 Worm   225 IKI--FSKFWDWHYSEIAHPIFLKKFDKI-----EYMAIFLLLLFDSAYMNISDDGVKLCQNIRK 282

  Fly   430 TILNSLN-----------------DVVYLLRHSSAVSHQQQLLLLLPSLRQADDILRRFWRGIAR 477
            .||..|.                 |.|.||..:.....::.:|....:|...:|          .
 Worm   283 VILRELQGYQSDKNCSRYRLAETVDTVRLLEKAEGKLQEESVLCEFHNLEIDED----------H 337

  Fly   478 DEVITMKKL 486
            .::..:||:
 Worm   338 KKIFQIKKI 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	32/96 (33%)
		NR_LBD	237..493	CDD:472173	51/278 (18%)
nhr-139	NP_504767.1	ZnF_C4	3..66	CDD:197701	26/77 (34%)
		HOLI	154..315	CDD:214658	36/182 (20%)