Protein Alignment ERR and nhr-161

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_504765.2
• Gene: nhr-161 / 183178
• WormBaseID: WBGene00016364
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 352
• Identity: 79/352 - (22%)
• Similarity: 121/352 - (34%)
• Gaps: 117/352 - (33%)

  Fly   126 LCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYT-CPANNECEINKRRRKACQACRFQKCLL 189
            ||.:|...::.:|:|..||.||.|||:|.:....:.| |    .||.:   |..|:.||.:.||.
 Worm     2 LCKICDGPSTEYHFGCPSCRACAAFFRRYVNSPKQLTEC----NCETD---RVPCRYCRMKLCLK 59

  Fly   190 MGMLKEGVRLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTSL---CDVKILEVLNSYEPDALSV 251
            .||:...|        :||...||...|...::      |||:   .:.:|...|.:|.    .:
 Worm    60 AGMMISKV--------QQKRDNNPCRLSVSGLE------TTSIPLRNNDRIFTALENYR----WL 106

  Fly   252 QTPPPQVHTTSITNDEASSSSGSIK-LESSVVTPNGTCIFQNNNNNDPNEILSVLSDIYDKELVS 315
            ......||.||...........||. ::|.:|.......|......|..:..::.|:.|.|
 Worm   107 TKERKIVHKTSPAKKVNFYEYSSIAIIDSRIVWNLLERTFLELKVLDDIDKFNLFSNFYPK---- 167

  Fly   316 VIGW-------------------------AKQIPGFIDLPLNDQMKLLQVSWAEILTL------- 348
               |                         |:||..|    ..|.|..|::...|:|.:
 Worm   168 ---WTLFESAITALQKSDVHTFFAPNGKPAQQISKF----YKDCMTGLRMKDTEVLRIFEPYWNS 225

  Fly   349 ----------QLTFRSLPFNGKLCFATDVWMDEHLA------KECGYTEFYYHCVQIAQRMER-I 396
                      :|.|..:               ||:|      .:.|||.....||::..|..: |
 Worm   226 YYSHVAYPLFELKFDQM---------------EHMALLALMLMDPGYTNISDECVEMCHRFRKVI 275

  Fly   397 SPRREEYYL------------LKALLL 411
            ....:.|||            ::||||
 Worm   276 QMELKGYYLEKNSDPERILKVIEALLL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	30/91 (33%)
		NR_LBD	237..493	CDD:472173	45/237 (19%)
nhr-161	NP_504765.2	ZnF_C4	2..65	CDD:197701	25/69 (36%)
		Hormone_recep	114..306	CDD:459675	41/215 (19%)