Protein Alignment ldbr and dbr1

DIOPT Version :10

• Sequence 1: NP_996022.1
• Gene: ldbr / 38900
• FlyBaseID: FBgn0035838
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_988947.1
• Gene: dbr1 / 394544
• XenbaseID: XB-GENE-5851881
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 254/581 - (43%)
• Similarity: 332/581 - (57%)
• Gaps: 97/581 - (16%)

  Fly     1 MKIAVEGCAHGELERIYDTIEGIEKVGGTKIDLLLCCGDFQSTRNLEDLQTMAVPKKYLDMCSFY 65
            ||||||||.||||::||:||:.:||...||:||||||||||:.||..|::.||||:||..|.:||
 Frog     1 MKIAVEGCCHGELDKIYETIQFLEKKENTKVDLLLCCGDFQAVRNEGDMKCMAVPQKYRQMQTFY 65

  Fly    66 KYYSGELVAPVLTIFIGGNHEASNYLQELPYGGWVAPNIYYLGYAGVVNVNGVRIAGISGIFKGH 130
            ||||||.:||:||||||||||||||||||||||||||||||:||||||...||||.|||||||.|
 Frog    66 KYYSGEKLAPILTIFIGGNHEASNYLQELPYGGWVAPNIYYVGYAGVVKYRGVRIGGISGIFKSH 130

  Fly   131 DFLRGHHEFPPYTDSTCRSVYHVRQLEVFRLKQISGRVDIFLSHDWPTGIYEYGNKAQLLRKKPF 195
            |:.:||.|.|||:..|.||.||||.:|||||||:...:|||:|||||..||.||||.|||:||.|
 Frog   131 DYRKGHFERPPYSKDTVRSAYHVRNIEVFRLKQLKEPMDIFMSHDWPRSIYHYGNKKQLLKKKDF 195

  Fly   196 FAADMESGKLGSQPLEELLKAVQPAYWFAAHLHCKFAALVPHNHSQKLGDAESSSSSSSSEDEDE 260
            |..::|:..|||....|||..:||:|||:||||.||||.:.|              .::.|.|
 Frog   196 FRQEVENNTLGSPAASELLLHIQPSYWFSAHLHVKFAAFMQH--------------QTNVEGE-- 244

  Fly   261 EREKVKKAAPVPPPSKSVPVTKFLALDKCLPRRAFLQVVEVPSDPIEGTPR-LEYDAEWLAILHS 324
                :.||            |||||||||||.|.|||:|:|..||  |.|. ||||.||||:|.:
 Frog   245 ----IPKA------------TKFLALDKCLPHREFLQIVDVEHDP--GKPDCLEYDLEWLAVLKA 291

  Fly   325 TNHLISVKENYYYLPGKKAGEFTERSNFTPTEE-ELEAVTAKFQKLQVPENFERTVPAFDPAEQS 388
            |..|:::....:.:|....  ...|.:|:.:|: :.|.:......:::|.||..|...:|| ...
 Frog   292 TKDLLNITSKTWNMPENNG--LHSRWDFSASEKTKREILDDLGHDIKIPCNFCMTTACYDP-NNP 353

  Fly   389 DYK----HMFVDQPKVQLNPQSNTFCATLGIDDPLCLVL---------LANGLDLPAVGATE--- 437
            .||    |:        :|||:..|||.||:.|....:.         :....:..::|:.|
 Frog   354 QYKRVATHI--------VNPQTTEFCARLGLVDLNAKIRQHEEEGDIDITEDNEADSIGSAEDPG 410

  Fly   438 --CKDRETKSSKLQ----AVEED-------VAEPLVTPTK-------------RKLNLSLPAPTT 476
              ..|....|:.:.    |:|:|       :||.|..|:.             |.|..|:...:.
 Frog   411 EYSTDTSLLSTSINPDEIALEDDDDQEDEGMAEKLGEPSPDYTPDLSINFSNIRVLPDSMAVSSD 475

  Fly   477 AAADTTDENVIDLPEEEAEEAIIATETPHVEEPASVPASPNVK---KLKRRNQNIYQAQED 534
            .|.|:|::. :|..|....|.    |......|....::.|..   |:|||||.||||::|
 Frog   476 DATDSTNDE-LDRSESSQTEG----EGKQSNRPLKRMSNENGSGGVKIKRRNQAIYQAKDD 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ldbr	NP_996022.1	MPP_Dbr1_N	3..296	CDD:277322	175/292 (60%)
		DBR1	281..418	CDD:461518	54/142 (38%)
dbr1	NP_988947.1	MPP_Dbr1_N	3..264	CDD:277322	175/292 (60%)
		Lariat recognition loop. /evidence=ECO:0000250|UniProtKB:C4M1P9	124..154		18/29 (62%)
		DBR1	246..379	CDD:461518	56/157 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	388..457		11/68 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	470..534		20/67 (30%)