DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34039 and Commd4

DIOPT Version :9

Sequence 1:	NP_001034012.2	Gene:	CG34039 / 3885643	FlyBaseID:	FBgn0054039	Length:	198	Species:	Drosophila melanogaster
Sequence 2:	NP_079693.1	Gene:	Commd4 / 66199	MGIID:	1913449	Length:	199	Species:	Mus musculus

Alignment Length:	208	Identity:	68/208 - (32%)
Similarity:	108/208 - (51%)	Gaps:	32/208 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFRFCGEGDCPDWVLAEIISTLSNLSIENLEQLSDLVAQRICGETFEEAKIKSLTSTLTNEG-- 63
            |:|||||:.||||||||| ||||:.:|...|..|...|.:.:.|:..:..||..||:....|.
Mouse     1 MRFRFCGDLDCPDWVLAE-ISTLAKISSVKLRLLCSQVLKELLGQGIDYEKILKLTADAKFESGD 64

  Fly    64 -KTAVACINFMLTSAARYSCSESIFGEEIQQLGLPKDHAAAMCRVLQKHSATIRQTLINKSFRIN 127
             |..||.::|:|:|||::|........|:|||||||:||.::||..::..:.:::.|...|.|:|
Mouse    65 VKATVAVLSFILSSAAKHSVDSDSLSSELQQLGLPKEHATSLCRCYEEKQSPLQEHLRACSLRVN 129

  Fly   128 ELTSVRDISTPGQTPPNYATLELKISQELVDGLPKDTTHV----------------LNIDRTQMK 176
            .|.||.            ..::..:|..|:..:.:...|:                :::...:.:
Mouse   130 RLASVG------------WRVDYTLSSSLLHSVEEPMVHLQLQVVPAPGTQAQPVSMSLSADKFQ 182

  Fly   177 ALLAELKLARDVM 189
            .||||||.|:.:|
Mouse   183 VLLAELKQAQTMM 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34039	NP_001034012.2	HCaRG	23..190	CDD:284632	50/186 (27%)
Commd4	NP_079693.1	Commd4	25..198	CDD:240100	49/183 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842060
Domainoid	1	1.000	99	1.000	Domainoid score	I7137
eggNOG	1	0.900	-	-		E1_28K8D
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9865
Inparanoid	1	1.050	106	1.000	Inparanoid score	I4912
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54538
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007165
OrthoInspector	1	1.000	-	-		oto92131
orthoMCL	1	0.900	-	-		OOG6_105743
Panther	1	1.100	-	-	LDO	PTHR16231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3436
SonicParanoid	1	1.000	-	-		X5270
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790