Protein Alignment Egfrap and sh2d5

DIOPT Version :10

• Sequence 1: NP_001033991.1
• Gene: Egfrap / 3885637
• FlyBaseID: FBgn0053993
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001349485.1
• Gene: sh2d5 / 541529
• ZFINID: ZDB-GENE-050327-67
• Length: 410
• Species: Danio rerio
• Alignment Length: 386
• Identity: 80/386 - (20%)
• Similarity: 126/386 - (32%)
• Gaps: 141/386 - (36%)

  Fly   121 PQPGS---------HPHPHHLRSP----SSEEDNS---------PTEMNNCRRLVDKPPLVKRLT 163
            |||||         ..|....||.    |...|:|         .|::.:.:....|..:..|.:
Zfish     7 PQPGSVWNMGETAGREHGTVTRSAEYIGSFPVDDSCLDDQIQQLHTQLKSLKNCKSKRTVSLRFS 71

  Fly   164 M-GIGLLRGTEDSRPLMHSTCGSSLTSGSGCGSTQTISDG------------------------- 202
            : |:.:....|.:..:.|:.|..||       ||...||.
Zfish    72 VKGVKVYDEDETTLLMAHAMCRVSL-------STARPSDAQFAFASHNPGNSDAQLYCHLFRARH 129

  Fly   203 -----YVNEAICEP-DKYVASKFGDSCRQ--------------------SLSALES----ATQRL 237
                 ::|..:|.. ..|...|..:..::                    |:|||.|    .||.|
Zfish   130 ARAAQFLNLLLCRCFQLYFLEKHPEEAQEECSGKKPSRAPSLLNQGFPLSVSALVSFRRAPTQGL 194

  Fly   238 QVELPAASKKYLRETCSANSSPKLFPGHS-------ALRLDNL---------------------- 273
               ||.| |.:.:::....|||:..|..|       |:|...|
Zfish   195 ---LPGA-KLFSQQSTEQVSSPEEGPTSSPTIVRKMAIRTKELRSGAYRSFTFTPLKQRHLQDKL 255

  Fly   274 -------------------SLAEQQE-LKGAAWFQAGIPREISLEALSRQSPGAFLVRQSSTKPG 318
                               ||||.:| |..|.|..||:..:.|...|:....||||:.....||.
Zfish   256 SAPQEKEQATAKACMSRAPSLAETEEALAQAVWCWAGVSSDCSSSLLADDVLGAFLLCPHPKKPN 320

  Fly   319 CFALSLRVPPPSPRVAHYLILRTQRGYKIKGFTKEFSSLKALITHHSVMPELLPVPLTLPR 379
            ..:|.:|.   |..:..|.|..::..::::....:|.||.||:.|::...:.|...|:..|
Zfish   321 RGSLIVRF---SSGLVTYAIKNSKGKFRLEKCHTDFESLAALMEHYTEFGDELECSLSCAR 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egfrap	NP_001033991.1	SH2	286..364	CDD:198173	21/77 (27%)
sh2d5	NP_001349485.1	PTB_tensin-related	25..152	CDD:269979	21/133 (16%)
		SH2	288..363	CDD:198173	21/77 (27%)