DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34041 and PH4alphaNE1

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_733374.1	Gene:	PH4alphaNE1 / 43625	FlyBaseID:	FBgn0039780	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	80/371 - (21%)
Similarity:	152/371 - (40%)	Gaps:	77/371 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 ILSVGLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATY 302
            :|.||||.: |:..:..:.:..|.:.:.::|..::.:.:.|.:.:.|::|.|:.::..|..:...
  Fly     5 VLLVGLIFL-LAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKE 68

  Fly   303 HIQFERDKLAIASSPVASYSLIHHMQSDWT----HWQLFLQEDPGKDELASLMSIKKY---LPTK 360
            |.....|.....::||..|.|:..:.:||:    ..||..:|       .:..:.::|   .|::
  Fly    69 HTMAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEE-------MNFNATREYGLSYPSQ 126

  Fly   361 NDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVAL 425
            .|:......:.::.:.|.:....:|.|::.|  .||.|.                 ||.:||..|
  Fly   127 EDVEGAALALVRLQSTYKLDVAQVAQGILNG--VKYGSD-----------------MSWQDCFEL 172

  Fly   426 SDHSMEMKDYNKSKEWLNVAISMLESSAYWDP--IVPSA---DLYLKLAEVYVKQ----QNWTLA 481
            .....||:|||.:|.||..::..|.......|  :.|::   .:.|...|...|.    .::..|
  Fly   173 GQQLFEMEDYNNTKVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTA 237

  Fly   482 LETVEFALKSNPRNAQLIRMQKRLSYHILLG-----PPKS------PK------LNIENNDYRLR 529
            .|..:..|:.:|:..:        ::|  ||     ||:.      ||      |:.|...|...
  Fly   238 FELSQRVLQFDPKRIR--------NWH--LGDKGTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKV 292

  Fly   530 KNGSLYCFYDTKIRTFYS-------LLAPIKAEVLFIDPLVILYHE 568
            ..|.::.....::|..||       .|||:|.|...:||.|..:|:
  Fly   293 CRGEVHPIVRQELRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHD 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	24/135 (18%)
		TPR repeat	452..491	CDD:276809	8/47 (17%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	24/135 (18%)
PH4alphaNE1	NP_733374.1	P4Hc	341..511	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840