DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and PH4alphaSG2

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	80/366 - (21%)
Similarity:	153/366 - (41%)	Gaps:	78/366 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 LSVGL--IIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLAT 301
            |.:|:  :|:::..:|.|...|:...:  ::.:::|.::....:|:   |::.|.:|    ....
  Fly     7 LYIGIFQLIIWVGVANGEFYSSVDSMQ--DLAQVEEELLNATRSYV---ESQQKQLD----FYRR 62

  Fly   302 YHIQFERDKLAIASS---------PVASYSLIHHMQSDWTH--WQLFLQEDPGKDELASLMSIKK 355
            |..|.:|:.....|.         |:.::.||..:..||..  ::..|..:..::..|.:..:.:
  Fly    63 YVEQIKREHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSR 127

  Fly   356 YL--PTKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMS 418
            .|  |.::::.....|::::...|.:...|:|:|:|.|  ..|.|.                 :.
  Fly   128 DLGYPDQSELQGAIKGLARLQKVYNLATSDLADGIIGG--LNYGSD-----------------LR 173

  Fly   419 LRDCVALSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTL--- 480
            .|:|..:.....::.:|.:|.|||.||..:|.:|...:   ..||.||.....|....|:.|
  Fly   174 WRECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPREE---KDADHYLSDIREYASMANFELGNP 235

  Fly   481 --ALETVEFALKSNP-RNAQLIRMQKRLSYHILLGPPKSPKLNIE-------NNDYRL------- 528
              |...:...|:|.| .:||  :.||.|...:       |..|::       :|..||
  Fly   236 KKAARLLSQILESQPTHSAQ--QTQKYLESRV-------PGKNVQETKPSWFSNYTRLCQGRRLP 291

  Fly   529 --RKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYH 567
              |....|.|:.|.| |..|..|||::.|.:.:||.:.:||
  Fly   292 EERSGDPLRCYLDGK-RHAYFTLAPLQVEPVHLDPDINVYH 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	23/141 (16%)
		TPR repeat	452..491	CDD:276809	10/43 (23%)
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	24/143 (17%)
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461979
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840