DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and CG18231

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	88/345 - (25%)
Similarity:	148/345 - (42%)	Gaps:	74/345 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 SKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQ--FERDKLAIASSPVASYS 322
            |.::::.:|:::|..:..::.|...|..|:|.: :|.||...|..|  || |:.....:|:.::|
  Fly    19 SITRLLKLLEMEEIFITNIKAYTNKLAEKVKNL-QAYIDSVDYEFQQSFE-DREKYVGNPINAFS 81

  Fly   323 LIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMTAQDIANG 387
            |:.....|...|..:.|:..|.:||.:|..|...:|.|.|::.....:.::...|.:.|.::|.|
  Fly    82 LVRRTHQDLPKWHNYSQQIVGMEELFALEEIIAKVPDKKDMAYSLGEMHRIEQIYDLEAIELARG 146

  Fly   388 VILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWLNVAI------ 446
            .|.|.|..:                   ..|:||||||.:|..:.:||.::..|..|||
  Fly   147 RIQGKQYDF-------------------RPSIRDCVALGEHKFKREDYQRASMWFRVAIKHEPEG 192

  Fly   447 -SMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETVEFALKSNPRNAQLIRMQKRLSYHIL 510
             :.:.:|...||.|....||.|...::              ..:||||  :..|...|::||..|
  Fly   193 NAEIINSILGDPKVNLYTLYAKSMLIF--------------GMIKSNP--SMTIAEAKKISYEAL 241

  Fly   511 ----LGPPKS--------------PKLNIEN---NDYRLRKNGSL------YCFYDTKIRTFYSL 548
                |...||              .::|:..   :||.:...|..      .|.|:..|..|..
  Fly   242 NKASLADIKSLLNELLSQTDDEIVYEMNVNKTKPSDYEIGCRGQFLRRRNHVCTYNFTITEFLK- 305

  Fly   549 LAPIKAEVLFIDPLVILYHE 568
            |||:|.|||..||.:::||:
  Fly   306 LAPLKQEVLNWDPYIVIYHD 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	33/130 (25%)
		TPR repeat	452..491	CDD:276809	7/38 (18%)
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528	33/130 (25%)
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461987
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840