DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and phy-2

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_502317.1	Gene:	phy-2 / 178170	WormBaseID:	WBGene00004025	Length:	539	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	76/382 - (19%)
Similarity:	139/382 - (36%)	Gaps:	111/382 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 CILSVGLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLAT 301
            |:|: ||....|..:.::.:|.|...|         :|...::.||.|...:|.       ||..
Worm     8 CLLA-GLAHADLFTAIADLQHMLGAEK---------DVTTIIDQYIEAERARLD-------DLRR 55

  Fly   302 Y-HIQFERDKLA------IASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASL------MSI 353
            | |....|:..|      ..::|:.:|.||..:.::|...:..:..:.....|.::      ..:
Worm    56 YAHEYVHRNAHAESVGPEFVTNPINAYLLIKRLTTEWKKVENIMLNNKASTFLKNITDNRVRSEV 120

  Fly   354 KKYLPTKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMS 418
            |  .|.:.|:|.....:.::.:.|.:...|::||:|.|                 |.:.|:  :|
Worm   121 K--FPGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGG-----------------EKVSNK--LS 164

  Fly   419 LRDCVALSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALE 483
            ..|...:...:...|||.....|:.||:..:|:..  .|.:...::...||....:|.|...||.
Worm   165 GHDTFEVGRSAYNQKDYYHCLMWMQVALVKIENEN--PPTIEEWEILEYLAYSLYQQGNVRRALS 227

  Fly   484 TVEFALK---SNPRNAQLIR------------------MQKRLSYHILLG------------PPK 515
            ..:...|   ::||....::                  :.||:.|..::.            ||.
Worm   228 LTKRLAKIAPNHPRAKGNVKWYEDMLQGKDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPV 292

  Fly   516 SPKLNIENNDYRLRKNGSLYCFYDTKIRTF------YSLLAPIKAEVLFIDPLVILY 566
            .||                   :..|:|.:      :..|||||.|:|..|||.:|:
Worm   293 EPK-------------------WKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLF 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	26/141 (18%)
		TPR repeat	452..491	CDD:276809	8/41 (20%)
phy-2	NP_502317.1	P4Ha_N	21..154	CDD:285528	28/150 (19%)
		TPR_16	169..240	CDD:290168	15/72 (21%)
		P4Hc	335..508	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810