DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and p4ha1b

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_999856.1	Gene:	p4ha1b / 100003675	ZFINID:	ZDB-GENE-030131-4089	Length:	536	Species:	Danio rerio

Alignment Length:	362	Identity:	78/362 - (21%)
Similarity:	142/362 - (39%)	Gaps:	80/362 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 SENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLAIASSP 317
            :.|....|..::.::|..::::|..|:.||...|.:|:.:.|....|.:..|...:|.......|
Zfish    17 AHNDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITATQDPEGFLGHP 81

  Fly   318 VASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMTAQ 382
            |.::.|:..:.|:|:..:..:.:|.....:::|...::|.||..|.:.....:.::.:.|.::|.
Zfish    82 VNAFKLMKRLNSEWSDLENLVLKDTTNGFISNLTVQRQYFPTDEDQTGAAKALLRLQDTYQLSAN 146

  Fly   383 DIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWLNVAIS 447
            .|::|.:.|                   :.::..|::.||..|...:....||..::.|:..|:|
Zfish   147 AISSGDLPG-------------------VVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALS 192

  Fly   448 MLESSAYWDPI--VPSADLYLKLAEVYVKQQNWTLALETVEFALKSNP----------------- 493
            .|:.... .||  |...| ||..| :| :|.....|||..:..||.:|
Zfish   193 QLDEGEE-SPIDKVTVMD-YLSYA-IY-QQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLE 253

  Fly   494 --------------------RNAQLIR----MQKRLSYHILL---GPPKSPKLNIENNDYRLRKN 531
                                |:||..|    :.:|..|..|.   |...:|           |:.
Zfish   254 KQRKAENEKKEEDQKRVLDKRDAQRKRSKDPLPERKKYERLCRGEGIKLTP-----------RRQ 307

  Fly   532 GSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
            ..|:|.|....|....||||:|.|..:..|.::.|||
Zfish   308 SRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHE 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	27/128 (21%)
		TPR repeat	452..491	CDD:276809	13/40 (33%)
p4ha1b	NP_999856.1	P4Ha_N	24..153	CDD:285528	27/128 (21%)
		TPR repeat	164..199	CDD:276809	9/34 (26%)
		TPR_16	168..238	CDD:290168	22/73 (30%)
		TPR repeat	204..234	CDD:276809	11/32 (34%)
		P4Hc	347..520	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810