Protein Alignment Octbeta3R and Adra1d

DIOPT Version :10

• Sequence 1: NP_001034048.2
• Gene: Octbeta3R / 3885573
• FlyBaseID: FBgn0250910
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_038488.4
• Gene: Adra1d / 11550
• MGIID: 106673
• Length: 562
• Species: Mus musculus
• Alignment Length: 398
• Identity: 117/398 - (29%)
• Similarity: 179/398 - (44%)
• Gaps: 94/398 - (23%)

  Fly   108 STVGPNITANGSDIAVDNQAELEESWLDLS-----------LLLLK-----GFIFSSIILAAVLG 156
            :|.|..:...||  ..|||:...|:....|           |::..     |...::.||.||.|
Mouse    45 ATGGSAVVGTGS--GEDNQSSTAEAGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAG 107

  Fly   157 NALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELSGGKWMFGPFMCNVYNSLDV 221
            |.|||:||..||.|:.:||||:|:||:||:|::...:.|:|::|:. |.|.||...|:|:.::||
Mouse   108 NLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVL-GFWAFGRTFCDVWAAVDV 171

  Fly   222 YFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILPALISFTPIFLGWYTTEEH 286
            ...|||||.||.||||||..:...|:||..||.:....:||.:|.:..::|..|: |||
Mouse   172 LCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPL-LGW------ 229

  Fly   287 LREISLHPDQ--CSFVVNKAYALISSSVSFWIPGIVMLVMYWRIFKEAIRQRKALSRTSSNILLN 349
              :..:.||:  |.......||:.||..||::|..|::|||.|::        .::|:::    .
Mouse   230 --KEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVY--------VVARSTT----R 280

  Fly   350 SVHMGHTQQPTSLS----YLHPSDCDLNATSAREETHSALSNLEDMLQPATDEDDDRDECDELRV 410
            |:..|..::|...|    .:|   |...||||:.             .|.|.....
Mouse   281 SLEAGIKREPGKASEVVLRIH---CRGAATSAKG-------------NPGTQSSKG--------- 320

  Fly   411 PSPPPRRLSRSSIDLRDLEQERYEKVTHTDSA----------PSMMALQQQQPSHN---QLQPPA 462
                  ...|||:.:|.|:..|.:|...|.:.          |....|    |..:   ||:|..
Mouse   321 ------HTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVL----PLGSLFPQLKPSE 375

  Fly   463 PVFNPQIW 470
            .||....|
Mouse   376 GVFKVIFW 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tmA_DmOct-betaAR-like	142..>338	CDD:320194	77/202 (38%)
		TM helix 1	142..167	CDD:320194	12/29 (41%)
		TM helix 2	174..200	CDD:320194	12/25 (48%)
		TM helix 3	213..243	CDD:320194	17/29 (59%)
		TM helix 4	255..278	CDD:320194	5/22 (23%)
		TM helix 5	302..331	CDD:320194	12/28 (43%)
		7tm_GPCRs	<1161..1234	CDD:475119
		TM helix 6	1167..1189	CDD:410628
		TM helix 7	1202..1227	CDD:410628
Adra1d	NP_038488.4	7tm_GPCRs	91..407	CDD:475119	107/350 (31%)
		TM helix 1	93..117	CDD:410628	12/23 (52%)
		TM helix 2	126..148	CDD:410628	10/21 (48%)
		TM helix 3	164..186	CDD:410628	11/21 (52%)
		TM helix 4	209..225	CDD:410628	4/15 (27%)
		TM helix 5	246..269	CDD:410628	10/22 (45%)
		TM helix 6	341..363	CDD:410628	3/25 (12%)
		TM helix 7	375..400	CDD:410628	3/9 (33%)