Protein Alignment CG7546 and ZK688.5

DIOPT Version :10

• Sequence 1: NP_001137904.1
• Gene: CG7546 / 38844
• FlyBaseID: FBgn0035793
• Length: 1346
• Species: Drosophila melanogaster
• Sequence 2: NP_001366828.1
• Gene: ZK688.5 / 176108
• WormBaseID: WBGene00022800
• Length: 1639
• Species: Caenorhabditis elegans
• Alignment Length: 1520
• Identity: 336/1520 - (22%)
• Similarity: 491/1520 - (32%)
• Gaps: 486/1520 - (31%)

  Fly     3 INLKVKTLDARIHEFSIDNELTIRQFKDQIAEKTNIAAENQRIIYQGRVLVDDKQVKEYDV-DGK 66
            |.:.:||||.|....:|..:.||:...|....:.||.:..||:|..||||...:.|:...: ||:
 Worm    21 IRVTLKTLDDREATVTIGLQDTIQSLIDLGRREMNIQSGFQRVIAGGRVLNSTQTVQAAGISDGQ 85

  Fly    67 VLHVAERPPFSQRGANARNNDEPMRTFRNVARP---------PPPG-MRTSPYFRALDGMLVGTM 121
            .:|:.:|.|   .|.|.|.|..|.|    ||.|         |||| :..||.|..   |:.|.:
 Worm    86 TVHLVDRGP---SGENDRPNVMPDR----VAGPRIINAIPGLPPPGFIFQSPAFAR---MIPGNV 140

  Fly   122 AIPVNNGPVAGTRPPPNRYPNS---SSFCINRITVALHMIDCADNIAAYLENPAVGLNN-----Q 178
            .||........|...|.|.|.|   :....:|::.     ||....|.    |..|.:|     |
 Worm   141 EIPTPPSQTQHTVVHPIRVPGSIAGTPVLTSRVSE-----DCVLQKAV----PYRGTSNSPNRPQ 196

  Fly   179 SLDILQRGRWSMESTVVEVGVSSTD----LPRNN---------NIIDMVQDAVTAALSHTGARNY 230
            :..  |...:..|..|::..|:..|    .||.:         |.|..:.|:....:|....:|.
 Worm   197 AAS--QTVTFPSEPNVIQWTVNIADDLIFRPREHFEQVVRETINNISFLSDSTRLGVSMKWNQNC 259

  Fly   231 T--VVQLPTVYTNENGETSQQRTAEAITSEGAAS--GAASNASGETTAATVIIEDVIET---DDE 288
            |  .|:||.|..:......::.....:.::..:.  .......| ..|||..:.::::|   |..
 Worm   260 TSLSVELPPVSPHIPSPALEKLDFLCLWTDHLSRFIDKLEEHDG-LVAATRHVLEMVKTRQFDQN 323

  Fly   289 VADGASDRSVTPTPE---------------------------PEAEGAVGGQQVTAAETPTSS-- 324
            ::..|.::.|....|                           .|...|:..|:.  .|||.:.
 Worm   324 LSQQARNQRVEALDEIVKHLEYQWAELSHMKDFERIRFRKNQTEEYRALKIQEY--PETPRNPHF 386

  Fly   325 -VGSANDAAAEGGNNSGPRRRTRPQVLAQVIQHYRGVQ---ARLAPFVDRYYEI-----LQNDPT 380
             :..|.|....|                 |::.:|..|   .||...:|...|:     :::..|
 Worm   387 YMRHALDIDVIG-----------------VMREFRKQQRRFTRLEDLLDDLNEVGAVKFIRDHIT 434

  Fly   381 FEESDTDGRENAQRIF-DRVSEAFHYLSHAQHAISDLMLD----------LSQPGPRVLTC---R 431
               ::.|.|..|..:| ..:....|.:||..|..:||.:.          |.|....|||.   .
 Worm   435 ---TEVDYRYQALSMFYCYIQRMRHQISHMTHLTADLDVSFITPSFPQRILPQYAVNVLTVPFPH 496

  Fly   432 PILV--------EQSGYIRSNNIFTP---------------NFLA--PPS----GIINEPFRNRA 467
            |..|        ||...|...:||.|               .:||  |||    .::.||.|...
 Worm   497 PATVIFKFQSSDEQPLTIPVTHIFEPPRMLSDVGGRYNGDYPYLAYHPPSVHMEVVLQEPRRIAE 561

  Fly   468 PGSASAAGTQTATTAGTQTPTSAGTPTAVAPSQAANLQAATDASRSAAAMAEIASRAAGAAAE-- 530
            |.....|.........||.....|         :.||.||||.. |..::.::. ||.....|
 Worm   562 PRPQILARPTPQQFVLTQEMNQGG---------SINLMAATDPI-SGLSLQDVL-RAQQEQVENL 615

  Fly   531 ------MAAGAASAAAGAANAAAAAARDLSSDQVE---DPIDEPMVG-------------PNAAG 573
                  :..|.....|.......|...|..|..||   .|..:...|             |:|.|
 Worm   616 FAQQPGIEGGRVRVTARPGRRFVATTGDAPSVPVETLPPPGSDQQPGTSRRFTTHRFNVQPDARG 680

  Fly   574 A--ETLA--------QEQQRLEMDHDHDQAQSETPER--------------ETR----PVPRLRV 610
            |  ||||        .|.||: ..:...:.::|..:|              :||    |:..||.
 Worm   681 AETETLAPFPVAIEPNELQRI-AKNIASRYRAEALQRIASSLTTRFNNESWDTRIQNMPLCTLRE 744

  Fly   611 YVPVTL----PPPNPQLEMARIIQAMVNGQRPNDIHVEFNAPNVMSI----NLPVHV----MTTV 663
            .|.:.|    ...|...|...::.|:|   |..::.|...|..:.|:    ..|.||    |.|.
 Worm   745 CVAIALEMLTSAGNTVNESKDLMLALV---RDEEVLVRAIAECIKSLFGRGEFPTHVARLIMPTN 806

  Fly   664 RQAPAAGSNETADQSASESSSPE------------SAPASGN------------------GESPN 698
            :.|.:....|:.| ...||.|.|            |.|.||:                  |..|:
 Worm   807 QTASSRNDYESVD-GVEESQSDEFDSMIVRVPSDISQPQSGDLRAIRERRQNRRQFLENRGRIPS 870

  Fly   699 AASTSSGTR-----------SGDQRANTLPTTATQTRSTSRPQIQIGG-------NNNWGGRIAP 745
            .:|..|.:.           :.|.||..||......|.|.|..:....       |:......|.
 Worm   871 TSSAPSTSENPPGPSFNSEDAADIRAGRLPLGTRPNRRTVRETVHPAAAARAESPNHISLTFTAT 935

  Fly   746 THTAFDRFLPCNSHHIREPEQLLQNNSTSRSTSTAPAGG--ATVVPPTSAAVTR----------- 797
            |||    |.|...       .|:..:|...|||..|.|.  ..||.||  ..||
 Worm   936 THT----FAPAGF-------PLMMASSNVPSTSAGPPGWPIRQVVSPT--PTTRGLFEFDLSGSS 987

  Fly   798 ----------PVTTGRIQRGSNTIRPMWSSRRQRPA---SEQLSNLG----PAAWAQAQTQTTHI 845
                      |..|.|......|::.  |..||...   |..:.|.|    ||  |.|..|...:
 Worm   988 DQPARSTPSPPAPTPRTTSAPATVQS--SPTRQESMDIDSPNVQNPGHVESPA--AIAARQAARV 1048

  Fly   846 PSAHVG--AGSTNGAGVGAGRVRPV---GGST----------------------------INR-- 875
            ..|.:.  |.:.||....:.|..|.   |.:|                            .||
 Worm  1049 ARARIDHLAATFNGDLADSRRQSPFVTPGPTTPLNDPRRRTVRVTQHVKPMVAIDPFMNCTNRHC 1113

  Fly   876 --DRLATRTAHVGGGS--TNGGLPSGR--RGRLQAATSRLSRHLPTQL------ANFLI------ 922
              :||||.| |:..|.  |...|...:  ..|:||....:.|. |.|:      .|:.|
 Worm  1114 EINRLATPT-HMADGDRFTLQSLQPDQEFEARIQALVPSIERR-PIQIHHEDEDYNYSIRRTQSG 1176

  Fly   923 ----NNMRNNAPTASVGSAVAAV-------------------GDTAAS---------------PS 949
                .|:.:..|  .|.:|:.::                   |..||:               |.
 Worm  1177 LLSFRNLEDFRP--FVKTAIRSLLAHCIDADTLFTMNMNNISGYQAANHTELLRMVKEHISRVPG 1239

  Fly   950 GEAAPIASTTPAAPLQTVLPTSTPT-PRGDSNNLRSQLRTFLNDSL-FVGVP--IN---EQTIPG 1007
            ..|     |..|:...|.:..||.| ||...|  ||.::...:..| |...|  ||   |..|||
 Worm  1240 SRA-----TRNASQNTTSVNQSTETSPREQMN--RSPVQEAADPRLAFSPFPPGINLEQEVLIPG 1297

  Fly  1008 AIGRALDWFGESLVYLPQYERPEYNSRDSVCNILRVSLRLIIELCNGAPAGVDSAQFEQ--SLKQ 1070
            .|       ...|.||..|.....|.|....      ...::||..|.....|.||..:  :...
 Worm  1298 QI-------ASLLTYLVDYMESSSNPRPPGI------FGFLLELTYGRLTRHDFAQLARRTTATN 1349

  Fly  1071 ICDQFRKRLYSVL---FLC--LGSANAELYWRQLMRLLCAPMRSNFRNEALQFLCIYID-----P 1125
            :..:|..::.:.:   :|.  .|.:|:||:          .:..|..|.. ||..|::.     |
 Worm  1350 VASEFEAQIRAHIRDNYLVGRTGLSNSELH----------GIAENLANNE-QFFAIFMSQNDQLP 1403

  Fly  1126 T-IPAQTDTVD-AQQFLVLRSIQAA 1148
            | .|...|..| |:.....|.|:.|
 Worm  1404 TSFPFGYDRNDFAEVVWAFRQIEIA 1428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7546	NP_001137904.1	Ubl_BAG6	3..73	CDD:340507	23/70 (33%)
		BAG6	350..457	CDD:463449	36/157 (23%)
ZK688.5	NP_001366828.1	UBQ	21..92	CDD:214563	23/70 (33%)