DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and cpb2

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001018539.2	Gene:	cpb2 / 100000935	ZFINID:	ZDB-GENE-050522-259	Length:	424	Species:	Danio rerio

Alignment Length:	312	Identity:	84/312 - (26%)
Similarity:	151/312 - (48%)	Gaps:	19/312 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSRE 100
            :.|.|.:.|..::::.:..||:.|.:..:..:.|.|.|.:..::........|.:::|..:|:||
Zfish   122 ERYHSLEDIYYWINKTSREHSDMVKVILIGSSSEKRPLYVLKLSGKREEEVNRAMWMDCGIHARE 186

  Fly   101 WMTPAAALLTIHKLVVEFAEN---SDLLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPNGGN- 161
            |:.||..:..::..:..:.:|   :::|...|.:|:.:.|||||:|:..|:|.||..|:.|..:
Zfish   187 WIAPAFCMWFVNYALAFYNQNTEITEMLNKMDIYILTVMNPDGYKYTWTTDRMWRKNRSENKDSY 251

  Fly   162 CFGTNLNRNFAVDW-NVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHT 225
            |.|.:|||||..:| ..|..:  ||||..|.|..|.||.|.:.|...:....::.:  :|||:|:
Zfish   252 CAGVDLNRNFDANWCTKGASD--DPCDPTYCGQFPESEPETQAVAKFLRSHKDTVK--LYLSIHS 312

  Fly   226 ANRSVFYPWVYDTDPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAGTF---GGTSMDYAL 287
            .::.:.:|:....:.:.|   |:|:...|.:...:....:...::|...|.|.   .|.|.|:|.
Zfish   313 YSQMLLFPYSCSYNEIPN---HNELFELVKEASTKIRRYYRNNYKYGSGAKTIYLAPGGSDDWAY 374

  Fly   288 LAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEK 339
            ..|...||.||:    :|..:|.|..|...|.....|:....|..|...|.|
Zfish   375 DLGIKYSFTFEL----QDRGQYGFLLPPSFIPQACNEALLAAKVIALHVINK 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	82/304 (27%)
cpb2	NP_001018539.2	Propep_M14	32..98	CDD:280416
cpb2	NP_001018539.2	M14_CPB2	120..420	CDD:199868	82/308 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750