Protein Alignment CG8560 and CPA1

DIOPT Version :10

• Sequence 1: NP_648120.3
• Gene: CG8560 / 38830
• FlyBaseID: FBgn0035781
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001859.1
• Gene: CPA1 / 1357
• HGNCID: 2296
• Length: 419
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 135/417 - (32%)
• Similarity: 207/417 - (49%)
• Gaps: 31/417 - (7%)

  Fly     9 LLLASVALAV----ENYDGYKIYDINARNAFEKQLLLRLSGNE--AYDFFDLPRSLDASSRVMVK 67
            ||:.||.|..    |::.|:::..|:..:..:.|.:..|...|  ..||:..|....:...|.|.
Human     4 LLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVP 68

  Fly    68 PEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSV---SFKAFHRHAEI 129
            ....:..:..||.:|::|    |...|.::...||.|.| :...||..||.   ::..:|...||
Human    69 FPSIQAVKIFLESHGISY----ETMIEDVQSLLDEEQEQ-MFAFRSRARSTDTFNYATYHTLEEI 128

  Fly   130 NAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAGALY 194
            ..:||.|.|..|..||....|.:||.|.|..:..:.|..|  :..:::|.|||:|||:..|..::
Human   129 YDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK--RPAIWIDTGIHSREWVTQASGVW 191

  Fly   195 VIHQLVENF---AANSELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRK-PISSACYGTDANRN 255
            ...::.:::   ||.:.:|...|..:..|.||||:.::|:|.|||||||. ...|.|.|.|.|||
Human   192 FAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRN 256

  Fly   256 FDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWGW-T 319
            :|..:|..||||..||:|:.|:.|.||.|.:.|.|.:.. .|..|.::::|||...|:||:|: |
Human   257 WDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKD-HGNIKAFISIHSYSQLLMYPYGYKT 320

  Fly   320 SALPSSWRDNDEVAQ---GGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFPVSITME 381
            ..:|    |.||:.|   ....|:.|..|||:..||....:|.|:|.:.|:.:. .....|.|.|
Human   321 EPVP----DQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYS-QGIKYSFTFE 380

  Fly   382 L-PAGGTGFNPSTSQIEGFVSETWVGI 407
            | ..|..||....|||.....|||:.:
Human   381 LRDTGRYGFLLPASQIIPTAKETWLAL 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_648120.3	Propep_M14	27..99	CDD:460505	15/73 (21%)
		M14_CP_A-B_like	123..414	CDD:349433	105/294 (36%)
CPA1	NP_001859.1	Propep_M14	26..100	CDD:460505	16/77 (21%)
		M14_CPA	117..417	CDD:349442	105/299 (35%)