DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AT1G53780

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_001185217.1	Gene:	AT1G53780 / 841815	AraportID:	AT1G53780	Length:	620	Species:	Arabidopsis thaliana

Alignment Length:	579	Identity:	159/579 - (27%)
Similarity:	238/579 - (41%)	Gaps:	141/579 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 CEGLS-VDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVTLD 497
            |:.|. :|.|  |....::|.|:   :.:..::: |||..|.|..|..|..|        |..|.
plant    39 CDDLDCLDGK--YTVFGKITSGF---ETLTCIAK-ASVDAKNRPNKDIRIRH--------TYILT 89

  Fly   498 D--DEPSEDAGETPVPDSKGE---ETAKDAEAEQKVD-GDKETSAKDKSEGDSPNIETPKKATNG 556
            |  |:|.:.|...|....||:   |...|.:..:..| .|.|....:.:|..:.....|.:....
plant    90 DPFDDPPQLAKMIPDASPKGKPKVEVTDDMQPREDWDIRDAEFDFLELNEAFAEMAANPVEVAIN 154

  Fly   557 NSSIKSPQKTPKK-------------------------------SAEKPTDAAMDVDNVAPEEPK 590
            :..|:...:.|:.                               |.|...:|..|:......|..
plant   155 SMIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEAS 219

  Fly   591 KA-VEQEVDSSSSNDEYYEPTLAELTNFLDN-----------PPEEF---ADPNF---------- 630
            :| .|||  ..|:..:..|..:.||...:.|           ||.::   :|...
plant   220 EAHFEQE--PYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVA 282

  Fly   631 -CLTLID--------FVDAIKV--------------------------------------MQPSA 648
             |..:|.        .||..|:                                      :.||.
plant   283 TCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSV 347

  Fly   649 KREGFITVPDTTWDDIGA----LEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGK 709
            ........||.|:.|||.    :|||||.::|    |:.:||...|||:..|.|||..||||.||
plant   348 TMMTVEEKPDATYSDIGGCKEQIEKIREVVEL----PMLHPEKFVRLGIDPPKGVLCYGPPGSGK 408

  Fly   710 TLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDG 774
            ||:|:|:||..|..||.|.|.||:..|:||..|.||..||.||:...|::||||.|::...|.|.
plant   409 TLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDD 473

  Fly   775 GDG-NNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERT 838
            |.| :|...|.:.::|.::||.:.|..:.:|.|||||||:|||:|||||||..:....|:...||
plant   474 GVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRT 538

  Fly   839 EILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSL---RQSLNNGD 894
            :|.|..|:...   ...|:..:.:|......||||:..:..:|.|:::   |:|:...|
plant   539 QIFKIHTRTMS---CERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKD 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	159/579 (27%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	19/36 (53%)
		AAA	699..830	CDD:278434	65/131 (50%)
AT1G53780	NP_001185217.1	cyclophilin	<4..95	CDD:294131	19/69 (28%)
		RPT1	228..616	CDD:224143	117/374 (31%)
		AAA	398..531	CDD:278434	65/132 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910