Protein Alignment smid and PEX1

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_196464.2
• Gene: PEX1 / 830746
• AraportID: AT5G08470
• Length: 1130
• Species: Arabidopsis thaliana
• Alignment Length: 1005
• Identity: 244/1005 - (24%)
• Similarity: 383/1005 - (38%)
• Gaps: 307/1005 - (30%)

  Fly    47 SRRKFGPFRQLVHQAFSIISESYNLDKVSSSE-------------EDC-VSEDSEPPP------- 90
            |..|..|.:.::...||.::...:|..|.|..             ..| |:||.|.|.
plant   286 SSAKKEPRQAILRLVFSDLAAKGHLMMVESLRLYLGAGLHSWVYLRGCNVNEDKEIPALSLSPCV 350

  Fly    91 -------------TNSVMNNMMNSLYSQPRKPLAPKPISEPIDI--------------SSG--DE 126
                         |:.:.||......|.|     |..:|..:|:              |.|  ||
plant   351 FKISENEKVLDKGTDRLGNNNSVRKSSHP-----PSGLSTYVDVVDWSVHDKVVTALSSEGLHDE 410

  Fly   127 NEDDSNTKTTNGDGVAAAAAPPPPTPAVQGSALKRL--------MEEVPEIAVAAKKVAKPNTIH 183
            ...|.|.|     |:               ..|.||        |..|..:.|::..|.:....|
plant   411 GNHDKNKK-----GL---------------EYLTRLWSLAQLDAMASVTGVDVSSLIVGRETFFH 455

  Fly   184 VSSSEAIQKLHQVVGNRAKNLSEDAVPRSKDHRNVPGLYQQLHQNQ------------SRDRLRK 236
            . ....::....:.|..:.|...::..:.| |..:..||.....::            |.||..|
plant   456 F-EVRGLESYKSIDGQPSVNDRWESGKKDK-HTPLEILYVMTVSDESLLGDKFAGYDLSLDRSEK 518

  Fly   237 FKRDLEVQHPTESFR---------------------DIGG---MDSTLKELCEMLIHIKSPE--F 275
            ....:.::...|...                     ||..   |...:.::.:.:..:.||.  .
plant   519 SDNVVHIEPVLEKMNLGEPIYLKSAKETHCNKGVSPDISSLTWMGPIVSDVIKRMTVLLSPAAGM 583

  Fly   276 YFQLGLLPSRG-LLLHGPPGCGKTFLARAISGQLKMPLMEIPATELIGGISGESEERIR------ 333
            :|....:||.| :|::||||.|||.||||.:...: ...::.|..::...|..:.|:::
plant   584 WFSKFKIPSPGHILIYGPPGSGKTILARAAAKYFE-EQKDLLAHVILVSCSTLALEKVQHIHHVL 647

  Fly   334 -EVFDQAIGYSPCVLFIDEIDAI-------GGNRQWASKDMERRIVSQLISSLDNLKANEFGQSV 390
             .|..:.:.::|.|:.:|::|:|       .|.:......|..:.::.:|......:.:..|...
plant   648 SSVIAEGLEHAPSVIILDDLDSIISSSSDTEGTQASVGVTMLTKFLTDVIDDYGEYRNSSCGIGP 712

  Fly   391 VVIAATTRP-DVLDPGLRRIGRFDHEIAIHIPSRKERREILR-------IQCEGLSVDPKLNYDK 447
            :...|:.:. :.:...|...||||..:.:..|:..||..||:       :.|   |.|..||
plant   713 LAFVASVQSLEQIPQTLSSSGRFDFHVQLAAPATSERGAILKHEIQKRLLDC---SEDILLN--- 771

  Fly   448 IAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVTLDDDEPSEDAGETPVPD 512
            :|....||...||..||.||...|:.|         |...|.|::...|..::
plant   772 LAAKCEGYDAYDLEILVDRAVHAAIGR---------HLPLESNISKYNLVKED------------ 815

  Fly   513 SKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKTPKKSAEKPTDA 577
                                                                             
plant   816 ----------------------------------------------------------------- 815

  Fly   578 AMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFVD-AI 641
                                                                |...:.|||. |:
plant   816 ----------------------------------------------------FTRAMHDFVPVAM 828

  Fly   642 KVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPG 706
            :.:..||...|.:     .|:|:|.:..|:..:|..:..|.|:|::..:..|...|.|||.||||
plant   829 RDITKSASEGGRL-----GWEDVGGVTDIKNAIKEMIELPSKFPKIFAKSPLRLRSNVLLYGPPG 888

  Fly   707 CGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKR 771
            ||||.:..|.|....:.|||||||||:|.|:|.||:|||..|.:|..:|||::|||||||:.|||
plant   889 CGKTHIVGAAAAACSLRFISVKGPELLNKYIGASEQAVRDIFSKAAAAAPCILFFDEFDSIAPKR 953

  Fly   772 SDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSE 836
              |.|......|:|||.|||:||||...||::.|||:|||::|||:|||||||.:|...||...|
plant   954 --GHDNTGVTDRVVNQFLTELDGVEVLTGVFVFAATSRPDLLDPALLRPGRLDRLLLCDFPSPPE 1016

  Fly   837 RTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGD---TNLD 898
            |.|||   |...::.::|||:||:.||..|||::||||..|:..|.:.::.:.||..|   |...
plant  1017 RLEIL---TVLSRKLLMADDIDLEPIALMTEGFSGADLQALLSDAQLAAVHEYLNREDKPETGTT 1078

  Fly   899 DLCVRSQHFQEALQQLRPSVNEQDR-KIYD 927
            .: :.....:....:.:|||:|.:: |:||
plant  1079 PI-ITDPLLKSIASKTKPSVSETEKQKLYD 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247	5/23 (22%)
		CDC48	<242..933	CDD:273521	196/740 (26%)
PEX1	NP_196464.2	PEX-1N	109..182	CDD:462729
		CDC48	<585..1117	CDD:273521	190/679 (28%)
		RecA-like_PEX1_r2	852..1009	CDD:410934	84/158 (53%)