DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and SPAC644.07

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_593875.1	Gene:	SPAC644.07 / 2543663	PomBaseID:	SPAC644.07	Length:	449	Species:	Schizosaccharomyces pombe

Alignment Length:	381	Identity:	95/381 - (24%)
Similarity:	141/381 - (37%)	Gaps:	94/381 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   550 PKKATN-----GNSSIKSPQKTPKKSAEKP-TDAAMDVDNVAPEEPKKAVEQ-----EVDSSSSN 603
            ||:.:|     .|..:|.||    .:.||| ...|..:.::.|...|..::.     :|:...||
pombe    80 PKRYSNQLAVESNRQLKMPQ----NAREKPDKQVANRIFSLVPGPGKHYIKYKKCWIQVERERSN 140

  Fly   604 DEYYEPTLAELTNFLDNPPEEFADPNFCLTLID---------FVDAIKVMQPSAKREGFI-TVPD 658
                  .|.:||.   ..|.|    ...||.:.         .::|.|.||.:.|.:..| |...
pombe   141 ------RLQDLTT---GTPWE----TITLTTLSRDRGIFSELLLEAQKFMQSAQKNKTTIYTAWA 192

  Fly   659 TTWDDIGALEKIREELKLAVLAP-------------VKYPEMLERLGLTAPSGVLLCGPPGCGKT 710
            |.|...|. .:.:..|...||..             ::..:..:..|:....|.||.||||.|||
pombe   193 TEWKPFGH-PRSKRMLSSVVLESNVKKMITDDVHDFLRNSQWYDTRGIPYRRGYLLYGPPGSGKT 256

  Fly   711 LLAKAIANEAGINF----ISVKG--PELMNMYVGESERAVRACFQRARNSAP-CVIFFDEFDSLC 768
            ....|:|.|...:.    ::.||  .:.:|..:.              |..| .|:..::.||..
pombe   257 SFLYALAGELDYDICVLNLAEKGLTDDRLNHLLS--------------NVPPKAVVLLEDVDSAF 307

  Fly   769 PKRSDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVG--F 831
            ..|...|:.........:.||..:|||.......|...||.|:.:|||::||||:|...|:|  .
pombe   308 QGRERSGEVGFHANVTFSGLLNALDGVTSSDERIIFMTTNHPEKLDPALVRPGRVDVKAYLGNAT 372

  Fly   832 PEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLR 887
            |||...    ..|...|..|.:||  ||.:|...             |..||.||:
pombe   373 PEQVRE----MFTRFYGHSPEMAD--DLSDIVCP-------------KNTSMASLQ 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	95/381 (25%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	12/49 (24%)
		AAA	699..830	CDD:278434	40/137 (29%)
SPAC644.07	NP_593875.1	BCS1_N	32..210	CDD:214980	34/147 (23%)
		AAA	242..372	CDD:214640	42/143 (29%)
		AAA	245..369	CDD:278434	40/137 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910