DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP003008

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_003436353.1	Gene:	AgaP_AGAP003008 / 1272945	VectorBaseID:	AGAP003008	Length:	412	Species:	Anopheles gambiae

Alignment Length:	397	Identity:	122/397 - (30%)
Similarity:	197/397 - (49%)	Gaps:	53/397 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   531 DKETSAKDKSEGDSPNIETPKKATN--------------------------GNSSIKSPQKTPKK 569
            |.|....||.|.|:   .|.|...|                          ....||..|:..||
Mosquito     3 DAEMVIPDKDESDT---RTMKDVVNPLEEPLEEDLYIKYKKLQKMLEFLEVQEEYIKDEQRNLKK 64

  Fly   570 S---AEKPTDAAMDVDNVAPEEPKKAVEQE--VDSSSSNDEYYEPTLAELTNFLDNPPEEFADPN 629
            .   |::.......|..|..:. .:||:|.  :..|::...||...|:.:...|..|....|...
Mosquito    65 EYLHAQEEVKRIQSVPLVIGQF-LEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHK 128

  Fly   630 FCLTLIDFVDAIKVMQPSAKREGFITV------PDTTWDDIGALEKIREELKLAVLAPVKYPEML 688
            ....|:|      |:.|.|  :..|::      ||..:.|||.::..::|::.||..|:.:.|:.
Mosquito   129 HSNALVD------VLPPEA--DSSISMLNADEKPDVQYSDIGGMDMQKQEIREAVELPLTHFELY 185

  Fly   689 ERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARN 753
            :::|:..|.|||:.||||||||:||||:|:.....||.|.|.|.:..|:||..|.||..|:.|:.
Mosquito   186 KQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKE 250

  Fly   754 SAPCVIFFDEFDSLCPKRSDGGDG-NNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAI 817
            ::|.:||.||.|::..||.|...| :....||:.:||.:|||.::...|.::.||||.|.:|||:
Mosquito   251 NSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPAL 315

  Fly   818 LRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQAS 882
            |||||||..:....|::.::..|....|   .:..|::||||::..|:.:..:|||:..:.::|.
Mosquito   316 LRPGRLDRKIEFPLPDRRQKRLIFSTIT---AKMNLSEDVDLEDFVARPDKISGADINAICQEAG 377

  Fly   883 MFSLRQS 889
            |.::|::
Mosquito   378 MHAVREN 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	122/397 (31%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	18/36 (50%)
		AAA	699..830	CDD:278434	61/131 (47%)
AgaP_AGAP003008	XP_003436353.1	PTZ00454	31..412	CDD:240423	113/366 (31%)
AgaP_AGAP003008	XP_003436353.1	AAA	196..329	CDD:278434	61/132 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910