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Protein Alignment MED4 and Med4

DIOPT Version :9

Sequence 1:	NP_648094.1	Gene:	MED4 / 38799	FlyBaseID:	FBgn0035754	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_080395.1	Gene:	Med4 / 67381	MGIID:	1914631	Length:	270	Species:	Mus musculus

Alignment Length:	261	Identity:	113/261 - (43%)
Similarity:	166/261 - (63%)	Gaps:	30/261 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 STKERLLLLIDDIEMIAKELIE----QAHQKISSTELVD-LLDLLVAKDEEFRKMLELAEEQAKV 65
            ||:||||..::|:|::::||||    ..:||:...|..: :|:||:.:|.:|:::::||..|.||
Mouse    25 STRERLLSALEDLEVLSRELIEMLAISRNQKLLQLEEENQVLELLIHRDGDFQELMKLALNQGKV 89

  Fly    66 EEAMDQLRAKVEVHDREIQKLQKSLKDAELILSTAIFQARQKLASINQANKRPVSSEELIKYAHR 130
            ...|..|..:||..|.:||:|||.||:||.||:||::||::||.||.:|.|..:||||:||||||
Mouse    90 HHEMQALEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHR 154

  Fly   131 ISSANAVSAPLTWCIGDLRRPYPTDIEMRNGLLGKSEQNINGGTVTHQNSGMPSEQQRTLSGSAG 195
            ||::|||.|||||..||.|||||||:|||:||||:    :|..:.:..|..:|.:
Mouse   155 ISASNAVCAPLTWVPGDPRRPYPTDLEMRSGLLGQ----MNNPSTSGVNGHLPGD---------- 205

  Fly   196 SGSGSGAGGEVPNAFQNQFNWNLGELHMTMGASGNT--VALE-----TRAQDDVEVMSTDSSSSS 253
                :.|.|.:|:....|:.|...::.:.|....::  ..||     ...:||||||||||||||
Mouse   206 ----ALAAGRLPDVLAPQYPWQSNDMSVNMLPPNHSSDFLLEPPGHNKENEDDVEVMSTDSSSSS 266

  Fly   254 S 254
            |
Mouse   267 S 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MED4	NP_648094.1	Med4	47..189	CDD:401849	72/141 (51%)
Med4	NP_080395.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		Med4	64..>189	CDD:401849	71/124 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..270		18/41 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Software error:

Can't use an undefined value as an ARRAY reference at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 1034.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-
Domainoid	1	1.000	-	-
eggNOG	1	0.900	-	-
Hieranoid	1	1.000	-	-