DRSC/TRiP Functional Genomics Resources

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Protein Alignment MED4 and med4

DIOPT Version :10

Sequence 1:NP_648094.1 Gene:MED4 / 38799 FlyBaseID:FBgn0035754 Length:258 Species:Drosophila melanogaster
Sequence 2:NP_001017883.1 Gene:med4 / 550582 ZFINID:ZDB-GENE-050417-438 Length:254 Species:Danio rerio


Alignment Length:264 Identity:116/264 - (43%)
Similarity:164/264 - (62%) Gaps:36/264 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 STKERLLLLIDDIEMIAKELIE----QAHQKISST-ELVDLLDLLVAKDEEFRKMLELAEEQAKV 65
            |||||||..:||:|::::||||    ...||:... |...:|:||:.:|:||:::::.|.||.:|
Zfish     9 STKERLLSTLDDLEVLSRELIEMLALSRSQKLPPPGEDTLILELLIQRDKEFQELMQTALEQGRV 73

  Fly    66 EEAMDQLRAKVEVHDREIQKLQKSLKDAELILSTAIFQARQKLASINQANKRPVSSEELIKYAHR 130
            .:.|..|..:||..|.:||:|||.||:||.||:||::||::||.||::|.|..:||:|:||||||
Zfish    74 HQEMQSLEKEVEKRDSDIQQLQKQLKEAEHILATAVYQAKEKLKSIDKARKGSISSKEIIKYAHR 138

  Fly   131 ISSANAVSAPLTWCIGDLRRPYPTDIEMRNGLLGK-SEQNINGGTVTHQNSGMPSEQQRTLSGSA 194
            ||::|||.|||.|..||.|||||||:|||:|:||. |..:.||     .|..:|.:         
Zfish   139 ISASNAVCAPLNWVPGDPRRPYPTDLEMRSGMLGNMSNMSTNG-----VNGHLPGD--------- 189

  Fly   195 GSGSGSGAGGEVPNAFQNQFNWNLGELHMTMGA----SGNTVALE-----TRAQDDVEVMSTDSS 250
                 :.|.|.:|:....|:.|.  ...::||.    .||...||     ...:||||.||||||
Zfish   190 -----ALAAGRLPDVLTPQYPWQ--STDVSMGILPPHHGNDFGLEPPGHNKENEDDVEAMSTDSS 247

  Fly   251 SSSS 254
            ||||
Zfish   248 SSSS 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MED4NP_648094.1 Med4 47..189 CDD:401849 71/142 (50%)
med4NP_001017883.1 Med4 49..>175 CDD:401849 69/125 (55%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 215..254 18/37 (49%)

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