DRSC/TRiP Functional Genomics Resources

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Protein Alignment: MED4 and MMACHC

Sequence 1:NP_648094.1 Gene:MED4 FlyBaseID:FBgn0035754 Length:258 Species:Drosophila melanogaster
Sequence 2:NP_056321.2 Gene:MMACHC HGNCID:24525 Length:282 Species:Homo sapiens

Alignment Length:99 Identity:20/100 (20%)
Similarity:39/100 (39%) Gaps:22/100 (22%)


  Fly    23 KELIEQAHQKISSTELVDLLDLLVAKDEEFRKMLELAEEQAKVEEAMDQLRAKV----EVHDREI 83
            |..::..|.::    |.|.:|..|            |....:|.|::.:|:.::    |||....
Human    64 KPFLQSCHLRM----LTDPVDQCV------------AYHLGRVRESLPELQIEIIADYEVHPNRR 112

  Fly    84 QKLQKSLKDAELILSTAIFQARQKLASINQANKR 117
            .|:  ..:.|..:...|.:..||.:.:....|:|
Human   113 PKI--LAQTAAHVAGAAYYYQRQDVEADPWGNQR 144

Known Domains:


GeneSequenceDomainRegion External IDIdentity
MED4NP_648094.1 Med4 47..189 CDD:287038 14/76 (18%)
MMACHCNP_056321.2 MMACHC 20..234 CDD:293295 20/100 (20%)
Substrate binding. {ECO:0000244|PDB:3SC0, ECO:0000244|PDB:3SOM, ECO:0000269|PubMed:21697092, ECO:0000269|PubMed:22642810} 115..118 0/5 (0%)
Substrate binding. {ECO:0000244|PDB:3SC0, ECO:0000244|PDB:3SOM, ECO:0000269|PubMed:21697092, ECO:0000269|PubMed:22642810} 129..131 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG4552
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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