Protein Alignment Neos and ncoa5

DIOPT Version :10

• Sequence 1: NP_523955.1
• Gene: Neos / 38795
• FlyBaseID: FBgn0024542
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_005166217.1
• Gene: ncoa5 / 447849
• ZFINID: ZDB-GENE-040912-155
• Length: 622
• Species: Danio rerio
• Alignment Length: 476
• Identity: 99/476 - (20%)
• Similarity: 181/476 - (38%)
• Gaps: 161/476 - (33%)

  Fly    12 TKDPALAKSRIFLGNLPVC--TREELVSICQPYGKVLGSMVQKNYGFVQFETEELANKAASALHK 74
            :.||...:.|||:||||..  .::::..:.:||||:....:.:.|||||||..|.|..|.:..:.
Zfish    19 SNDPRDLERRIFVGNLPTAHMAKKDMEDLFRPYGKIQALSLFRGYGFVQFERLEDAEAAKAGHNG 83

  Fly    75 STFKQNMLTVRNASIK--SKAANAIAKRNSNQGGQVTV-----------------QGGLVMSAAA 120
            ..::...|.|..|:.:  :|:.::..:|.|:..|:...                 :....|.|::
Zfish    84 RVYRGYKLDVNMAAERRQNKSRSSPPRRPSSSYGESREPRPRSRSPVHARDSRYHRESREMRASS 148

  Fly   121 -------------------------AAAGQPLIN------------------------------- 129
                                     :...:|.:.
Zfish   149 RESRPSSTREHEDRPPAEERYRGSESREKEPSLREEGYDRYYRGDYDYYRKKDEAYSDRYRDPWN 213

  Fly   130 --------------------------------------DCEIIVQNRENTKYAEYIEERLKNSSL 156
                                                  ||.:||.|:...:|||.:..::::..:
Zfish   214 GRREPEEERIRPEERRRNELYRQYYEELQKRYDIERPVDCSVIVVNKLQKEYAETVGRKVRDLGM 278

  Fly   157 RVDVLFPNEDVLLGKVLANISSRGCLYAVLVTPQHEEHNSITVNILYGVPAEHRNMPLEDAITLI 221
            .||::|.|.:|.|.:.|.::|.....:|:::|.||:.|.|.|||||:|.|.||||||::||:.|:
Zfish   279 VVDLIFLNTEVSLTQALEDVSRARTPFAIIITQQHQVHRSCTVNILFGTPQEHRNMPIQDAMVLV 343

  Fly   222 STDFRL------KKQRD-----AVVLPPSTSIHKGQRR-HPQEMQGLLERLADNHPLTASQYEVI 274
            :.:|..      .|:||     |..:.....:.:.:|. ||..:...:..|::...:|..:...:
Zfish   344 AHNFETFKVEHRAKERDEIARKAAKMADDVLMREHEREGHPVSVLTAITLLSEGRFMTPEELARL 408

  Fly   275 LKYLEGEREEQLK--REVGEANALAKLKAPDP--------------------------------E 305
            ::||..:|:..::  .:.|...:.|.|:...|                                :
Zfish   409 IEYLRDKRDRLVRSTTDAGPHPSSATLEPSQPTQAISAPAQPTYSSLSLQTSHLTPASAPAQTNQ 473

  Fly   306 IELQKKILSIMNKPAVTDVTS 326
            .|||.|||||.|..:.:.|.|
Zfish   474 QELQAKILSIFNSGSGSSVAS 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neos	NP_523955.1	U2AF_lg	<19..149	CDD:273727	39/244 (16%)
		RRM_SF	20..78	CDD:473069	21/59 (36%)
ncoa5	XP_005166217.1	RRM_hnRNPC_like	27..94	CDD:409778	22/66 (33%)
		PLN03209	<424..587	CDD:178748	15/71 (21%)