Protein Alignment Neos and ncoa5

DIOPT Version :8

• Sequence 1: NP_001261502.1
• Gene: Neos / 38795
• FlyBaseID: FBgn0024542
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_005166217.1
• Gene: ncoa5 / 447849
• ZFINID: ZDB-GENE-040912-155
• Length: 622
• Species: Danio rerio
• Alignment Length: 476
• Identity: 99/477 (21%)
• Similarity: 181/477 (38%)
• Gaps: 161/477 (34%)

  Fly    12 TKDPALAKSRIFLGNLPVC--TREELVSICQPYGKVLGSMVQKNYGFVQFETEELANKAASALHK 74
            :.||...:.|||:||||..  .::::..:.:||||:....:.:.|||||||..|.|..|.:..:.
Zfish    19 SNDPRDLERRIFVGNLPTAHMAKKDMEDLFRPYGKIQALSLFRGYGFVQFERLEDAEAAKAGHNG 83

  Fly    75 STFKQNMLTVRNASIK--SKAANAIAKRNSNQGGQVTV-----------------QGGLVMSAAA 120
            ..::...|.|..|:.:  :|:.::..:|.|:..|:...                 :....|.|::
Zfish    84 RVYRGYKLDVNMAAERRQNKSRSSPPRRPSSSYGESREPRPRSRSPVHARDSRYHRESREMRASS 148

  Fly   121 -------------------------AAAGQPLIN------------------------------- 129
                                     :...:|.:.
Zfish   149 RESRPSSTREHEDRPPAEERYRGSESREKEPSLREEGYDRYYRGDYDYYRKKDEAYSDRYRDPWN 213

  Fly   130 --------------------------------------DCEIIVQNRENTKYAEYIEERLKNSSL 156
                                                  ||.:||.|:...:|||.:..::::..:
Zfish   214 GRREPEEERIRPEERRRNELYRQYYEELQKRYDIERPVDCSVIVVNKLQKEYAETVGRKVRDLGM 278

  Fly   157 RVDVLFPNEDVLLGKVLANISSRGCLYAVLVTPQHEEHNSITVNILYGVPAEHRNMPLEDAITLI 221
            .||::|.|.:|.|.:.|.::|.....:|:::|.||:.|.|.|||||:|.|.||||||::||:.|:
Zfish   279 VVDLIFLNTEVSLTQALEDVSRARTPFAIIITQQHQVHRSCTVNILFGTPQEHRNMPIQDAMVLV 343

  Fly   222 STDFRL------KKQRD-----AVVLPPSTSIHKGQRR-HPQEMQGLLERLADNHPLTASQYEVI 274
            :.:|..      .|:||     |..:.....:.:.:|. ||..:...:..|::...:|..:...:
Zfish   344 AHNFETFKVEHRAKERDEIARKAAKMADDVLMREHEREGHPVSVLTAITLLSEGRFMTPEELARL 408

  Fly   275 LKYLEGEREEQLK--REVGEANALAKLKAPDP--------------------------------E 305
            ::||..:|:..::  .:.|...:.|.|:...|                                :
Zfish   409 IEYLRDKRDRLVRSTTDAGPHPSSATLEPSQPTQAISAPAQPTYSSLSLQTSHLTPASAPAQTNQ 473

  Fly   306 IELQKKILSIMNKPAVTDVTS 326
            .|||.|||||.|..:.:.|.|
Zfish   474 QELQAKILSIFNSGSGSSVAS 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neos	NP_001261502.1	RRM	<19..>117	CDD:223796	29/119 (24%)
		RRM_SF	20..78	CDD:302621	21/60 (35%)
		HGTP_anticodon	130..221	CDD:294191	38/91 (42%)
ncoa5	XP_005166217.1	RRM	<1..168	CDD:223796	32/149 (21%)
		RRM_hnRNPC_like	27..94	CDD:240787	23/67 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C278148646
eggNOG	1	0.900				E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4303
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D421126at33208
OrthoFinder	1	1.000				FOG0002730
OrthoInspector	1	1.000				T128764
orthoMCL	1	0.900				OOG5_133491
Panther	1	1.100			LDO	PTHR23295
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5288
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	10	9.880