DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8641 and Rasd2

DIOPT Version :10

Sequence 1:NP_648073.1 Gene:CG8641 / 38771 FlyBaseID:FBgn0035733 Length:434 Species:Drosophila melanogaster
Sequence 2:NP_083458.1 Gene:Rasd2 / 75141 MGIID:1922391 Length:266 Species:Mus musculus


Alignment Length:270 Identity:127/270 - (47%)
Similarity:175/270 - (64%) Gaps:28/270 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   156 CDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILD 220
            |..::| |||.||:|:||:||.||||||:|||..|||:.||||||:||||:|.|..:::||||||
Mouse    10 CTLNVP-AKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILD 73

  Fly   221 TSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKI 285
            |||.||||||||||.||||:||||||:||||||:||.||::.|||.|....|     |.|...::
Mouse    74 TSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKN-----KTKEAAEL 133

  Fly   286 PMILAGNKCDRD--FKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMT 348
            ||::.|||.|..  .:.|...|....::|.:||..| |.||::|..::::|:.||:::.||.||:
Mouse   134 PMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYF-EVSAKKNTNVNEMFYVLFSMAKLPHEMS 197

  Fly   349 PNHHRRLVSVFG---APSPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMR 410
            |..|.::...:|   .|.|.....:.|.|              |.|:|:|.|||||:.:||..::
Mouse   198 PALHHKISVQYGDAFHPRPFCMRRTKVAG--------------AYGMVSPFARRPSVNSDLKYIK 248

  Fly   411 SKTMALNEGE 420
            :|  .|.||:
Mouse   249 AK--VLREGQ 256

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8641NP_648073.1 Rhes_like 167..434 CDD:133343 122/259 (47%)
Rasd2NP_083458.1 Rhes_like 20..266 CDD:133343 122/259 (47%)
Effector region 48..56 6/7 (86%)
Interaction with GNB1, GNB2 and GNB3. /evidence=ECO:0000250 189..235 15/59 (25%)

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